1-Pirolin-4-hidroksi-2-karboksilatna deaminaza
1-Pirolin-4-hidroksi-2-karboksilatna deaminaza (EC 3.5.4.22, HPC deaminaza) je enzim sa sistematskim imenom 1-pirolidin-4-hidroksi-2-karboksilat aminohidrolaza (deciklizacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 1-Pirolin-4-hidroksi-2-karboksilatna deaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.4.22 | ||||||||
| CAS broj | 9054-77-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- 1-pirolidin-4-hidroksi-2-karboksilat + H2O 2,5-dioksopentanoat + NH3
Reference уреди
- ^ Singh, R.M.M. & Adams, E. (1965). „Enzymatic deamination of Δ1-pyrroline-4-hydroxy-2-carboxylate to 2,5-dioxovalerate (α-ketoglutaric semialdehyde)”. J. Biol. Chem. 240: 4344—4351. PMID 5845838.
- ^ Singh, R.M.M. & Adams, E. (1965). „Isolation and identification of 2,5-dioxovalerate, an intermediate in the bacterial oxidation of hydroxyproline”. J. Biol. Chem. 240: 4352—4356. PMID 5845839.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- 1-pyrroline-4-hydroxy-2-carboxylate+deaminase на US National Library of Medicine Medical Subject Headings (MeSH)
