4-Hidroksibutanoil-KoA dehidrataza
4-Hidroksibutanoil-KoA dehidrataza (EC 4.2.1.120) je enzim sa sistematskim imenom 4-hidroksibutanoil-KoA hidrolijaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 4-Hidroksibutanoil-KoA dehidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.120 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 4-hidroksibutanoil-KoA but-3-enoil-KoA + H2O
Ovaj enzim sadrži FAD i [4Fe-4S], gvožđe-sumporni kluster.
Reference уреди
- ^ Bartsch, R.G. & Barker, H.A. (1961). „A vinylacetyl isomerase from Clostridium kluyveri”. Arch. Biochem. Biophys. 92: 122—132. PMID 13687513.
- ^ Scherf, U., Sohling, B., Gottschalk, G., Linder, D. and Buckel, W. (1994). „Succinate-ethanol fermentation in Clostridium kluyveri: purification and characterisation of 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA Δ3-Δ2-isomerase”. Arch. Microbiol. 161: 239—245. PMID 8161284.
- ^ Scherf, U. & Buckel, W. (1993). „Purification and properties of an iron-sulfur and FAD-containing 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA Δ3-Δ2-isomerase from Clostridium aminobutyricum”. Eur. J. Biochem. 215: 421—429. PMID 8344309.
- ^ Muh, U., Cinkaya, I., Albracht, S.P. and Buckel, W. (1996). „4-Hydroxybutyryl-CoA dehydratase from Clostridium aminobutyricum: characterization of FAD and iron-sulfur clusters involved in an overall non-redox reaction”. Biochemistry. 35: 11710—11718. PMID 8794752.
- ^ Berg, I.A., Kockelkorn, D., Buckel, W. and Fuchs, G. (2007). „A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea”. Science. 318: 1782—1786. PMID 18079405.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- 4-hydroxybutanoyl-CoA+dehydratase на US National Library of Medicine Medical Subject Headings (MeSH)
