Almokalant

Almokalant
IUPAC ime
	4-(3-{Etil[3-(propan-1-sulfinil)propil]amino}-2-hidroksipropokss)benzonitril
Identifikatori
CAS broj	123955-10-2
ATC kod	None
PubChem	CID 3033962
ChemSpider	2298526
UNII	I9NG89L275
ChEMBL	CHEMBL362103
Hemijski podaci
Formula	C18H28N2O3S
Molarna masa	352,49 g·mol−1
	SMILES O=S(CCC)CCCN(CC)CC(O)COc1ccc(C#N)cc1; ;
	InChI InChI=1S/C18H28N2O3S/c1-3-11-24(22)12-5-10-20(4-2)14-17(21)15-23-18-8-6-16(13-19)7-9-18/h6-9,17,21H,3-5,10-12,14-15H2,1-2H3 ; Key:ZMHOBBKJBYLXFR-UHFFFAOYSA-N ;

Almokalant je lek koji se koristi za tretiranje aritmije.^[1] On je blokator kalijumovog kanala. Putem experimenata na pacovima je utvrđeno da ima teratogene efekte.^[2]

Reference уреди

^ Wiesfeld AC, Crijns HJ, Bergstrand RH, Almgren O, Hillege HL, Lie KI (1993). „Torsades de pointes with Almokalant, a new class III antiarrhythmic drug”. American heart journal. 126 (4): 1008—1011.
^ Signs of Almokalant - Teratogenic Agent, wrongdiagnosis.com

[1] Wiesfeld AC, Crijns HJ, Bergstrand RH, Almgren O, Hillege HL, Lie KI (1993). „Torsades de pointes with Almokalant, a new class III antiarrhythmic drug”. American heart journal. 126 (4): 1008—1011.

[2] Signs of Almokalant - Teratogenic Agent, wrongdiagnosis.com

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