Antranilat 3-monooksigenaza
Antranilat 3-monooksigenaza (EC 1.14.16.3, antranilatna 3-hidroksilaza, antranilatna hidroksilaza, antranilna hidroksilaza, antranilno kiselinska hidroksilaza) je enzim sa sistematskim imenom antranilat,tetrahidrobiopterin:kiseonik oksidoreduktaza (3-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju:
| Antranilat 3-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.16.3 | ||||||||
| CAS broj | 37256-79-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- antranilat + tetrahidrobiopterin + O2 3-hidroksiantranilat + dihidrobiopterin + H2O
Za rad ovog enzima je neophodan jon Fe2+.
Reference уреди
- ^ Jequier, E., Robinson, B.S., Lovenberg, W. and Sjoerdsma, A. (1969). „Further studies on tryptophan hydroxylase in rat brainstem and beef pineal”. Biochem. Pharmacol. 18: 1071—1081. PMID 5789774.
- ^ Nair, P.M. & Vaidyanathan, C.S. (1965). „Anthranilic acid hydroxylase from Tecoma stans”. Biochim. Biophys. Acta. 110: 521—531.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Anthranilate+3-monooxygenase на US National Library of Medicine Medical Subject Headings (MeSH)
