Bis-g-glutamilcistin reduktaza
Bis-g-glutamilcistin reduktaza (EC 1.8.1.13, NADPH2:bis-gama-glutamilcisteinska oksidoreduktaza) je enzim sa sistematskim imenom gama-glutamilcistein:NADP+ oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Bis-g-glutamilcistin reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.8.1.13 | ||||||||
| CAS broj | 117056-54-9 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 2 gama-glutamilcistein + NADP+ bis-gama-glutamilcistin + NADPH + H+
Ovaj enzim je visoko specifičan.
Reference уреди
- ^ Sundquist, A.R. & Fahey, R.C. (1988). „The novel disulfide reductase bis-γ-glutamylcystine reductase and dihydrolipoamide dehydrogenase from Halobacterium halobium: purification by immobilized-metal-ion affinity chromatography and properties of the enzymes”. J. Bacteriol. 170: 3459—3467. PMID 3136140.
- ^ Sundquist, A.R. & Fahey, R.C. (1989). „The function of γ-glutamylcysteine and bis-γ-glutamylcystine reductase in Halobacterium halobium”. J. Biol. Chem. 264: 719—725. PMID 2910862.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Bis-gamma-glutamylcystine+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
