Cu2+ eksportujuća ATPaza
Cu2+ eksportujuća ATPaza (EC 3.6.3.4, Cu2+-exporting ATPase) je enzim sa sistematskim imenom ATP fosfohidrolaza (Cu2+ eksport).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Cu2+ eksportujuća ATPaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.6.3.4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ova P-tip ATPaza podleže kovalentnoj fosforilaciji tokom transportnog ciklusa.
Reference уреди
- ^ Vulpe, C., Levinson, B., Whitney, S., Packman, S. and Gitschier, J. (1993). „Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPase”. Nat. Genet. 3: 7—13. PMID 8490659.
- ^ Petrukhin, K., Lutsenko, S., Chernov, I., Ross, B.M., Kaplan, J.H. and Gilliam, T.C. (1994). „Characterization of the Wilson disease gene encoding a P-type copper-transporting ATPase: genomic organization, alternative splicing, and structure/function predictions”. Hum. Mol. Genet. 3: 1647—1656. PMID 7833924.
- ^ Fagan, M.J. & Saier, M.H., Jr. (1994). „P-type ATPases of eukaryotes and bacteria: sequence analyses and construction of phylogenetic trees”. J. Mol. Evol. 38: 57—99. PMID 8151716.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Cu2+-exporting+ATPase на US National Library of Medicine Medical Subject Headings (MeSH)
