DATP(dGTP)—DNK purintransferaza
DATP(dGTP)—DNK purintransferaza (EC 2.6.99.1, DATP(dGTP)---DNA purinetransferase) je enzim sa sistematskim imenom dATP(dGTP):depurinisana-DNK purin transferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| DATP(dGTP)—DNK purintransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.99.1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (1) dATP + depurinated DNK dezoksiriboza trifosfat + DNK
- (2) dGTP + depurinated DNK dezoksiriboza trifosfat + DNK
Purinski ostatak se prenosi na apurinsko mesto, čime se formira normalna glikozilna veza.
Reference
уреди- ^ Deutsch, W.A. & Linn, S. (1979). „DNA binding activity from cultured human fibroblasts that is specific for partially depurinated DNA and that inserts purines into apurinic sites”. Proc. Natl. Acad. Sci. USA. 76: 141—144. PMID 218192.
- ^ Livneh, Z., Elad, D. and Sperling, J. (1979). „Enzymatic insertion of purine bases into depurinated DNA in vitro”. Proc. Natl. Acad. Sci. USA. 76: 1089—1093. PMID 375225.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- DATP(dGTP)---DNA+purinetransferase на US National Library of Medicine Medical Subject Headings (MeSH)
