Dihidroorotaza
Dihidroorotaza (EC 3.5.2.3, karbamoilaspartinska dehidraza, dihidroorotatna hidrolaza) je enzim sa sistematskim imenom (S)-dihidroorotat amidohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Dihidroorotaza | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifikatori | |||||||||
EC broj | 3.5.2.3 | ||||||||
CAS broj | 9024-93-5 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
|
- (S)-dihidroorotat + H2O N-karbamoil-L-aspartat
Reference уреди
- ^ Cooper, C. & Wilson, D.W. (1954). „Biosynthesis of pyrimidines”. Fed. Proc. 13: 194—194.
- ^ Lieberman, I. & Kornberg, A. (1954). „Enzymatic synthesis and breakdown of a pyrimidine, orotic acid. II. Dihydroorotic acid, ureidosuccinic acid, and 5-carboxymethylhydantoin”. J. Biol. Chem. 207: 911—924. PMID 13163076.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Dihydroorotase на US National Library of Medicine Medical Subject Headings (MeSH)