Fosfatidatna fosfataza
Fosfatidatna fosfataza (EC 3.1.3.4, fosfatno kiselinska fosfataza, kiselinska fosfatidilna fosfataza, fosfatno kiselinska fosfohidrolaza, PAP, Lipin) je enzim sa sistematskim imenom diacilglicerol-3-fosfat fosfohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Fosfatidatna fosfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.3.4 | ||||||||
| CAS broj | 9025-77-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 1,2-diacilglicerol 3-fosfat + H2O 1,2-diacil-sn-glicerol + fosfat
Ovaj enzim katalizuje Mg2+-zavisnu defosforilaciju 1,2-diacilglicerol-3-fosfata.
Reference уреди
- ^ Smith, S.W., Weiss, S.B. and Kennedy, E.P. (1957). „The enzymatic dephosphorylation of phosphatidic acids”. J. Biol. Chem. 228: 915—922. PMID 13475370.
- ^ Carman, G.M. & Han, G.S. (2009). „Phosphatidic acid phosphatase, a key enzyme in the regulation of lipid synthesis”. J. Biol. Chem. 284: 2593—2597. PMID 18812320.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Phosphatidate+phosphatase на US National Library of Medicine Medical Subject Headings (MeSH)
