Geranilgeranil difosfat reduktaza
Geranilgeranil difosfat reduktaza (EC 1.3.1.83, geranilgeranilna reduktaza, CHL P) je enzim sa sistematskim imenom geranilgeranil-difosfat:NADP+ oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Geranilgeranil difosfat reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.1.83 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- fitil difosfat + 3 NADP+ geranilgeranil difosfat + 3 NADPH + 3 H+
Ovaj enzim takođe deluje na geranilgeranil-hlorofil a. Reakcija se odvija u tri koraka.
Reference уреди
- ^ Soll, J., Schultz, G., Rudiger, W. and Benz, J. (1983). „Hydrogenation of geranylgeraniol : two pathways exist in spinach chloroplasts”. Plant Physiol. 71: 849—854. PMID 16662918.
- ^ Tanaka, R., Oster, U., Kruse, E., Rudiger, W. and Grimm, B. (1999). „Reduced activity of geranylgeranyl reductase leads to loss of chlorophyll and tocopherol and to partially geranylgeranylated chlorophyll in transgenic tobacco plants expressing antisense RNA for geranylgeranyl reductas”. Plant Physiol. 120: 695—704. PMID 10398704.
- ^ Keller, Y., Bouvier, F., d'Harlingue, A. and Camara, B. (1998). „Metabolic compartmentation of plastid prenyllipid biosynthesis—evidence for the involvement of a multifunctional geranylgeranyl reductase”. Eur. J. Biochem. 251: 413—417. PMID 9492312.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Geranylgeranyl+diphosphate+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
