Katepsin O
Katepsin O (EC 3.4.22.42, Cathepsin O) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Katepsin O | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.22.42 | ||||||||
| CAS broj | 162032-86-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Ovaj rekombinantni ljudski enzim hidrolizuje sintetičke endopeptidazne supstrate uključujući Z-Phe-Arg-NHMec i Z-Arg-Arg-NHMec
Katepsin O je lizozomalna cisteinska peptidaza iz familije C1 (papainske familije).
Reference уреди
- ^ Santamaría, I., Pendás, A.M. and López-Otín, C. (1998). „Genomic structure and chromosomal localization of a human cathepsin O gene (CTSO)”. Genomics. 53: 231—234. PMID 9790772.
- ^ Velasco, G., Ferrando, A.A., Puente, X.S., Sanchez, L.M. and López-Otín, C. (1994). „Human cathepsin O. Molecular cloning from a breast carcinoma, production of the active enzyme in Escherichia coli, and expression analysis in human tissues”. J. Biol. Chem. 269: 27136—27142. PMID 7929457.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Cathepsin+O на US National Library of Medicine Medical Subject Headings (MeSH)
