Metilkrotonoil-KoA karboksilaza
Metilkrotonoil-KoA karboksilaza (EC 6.4.1.4, metilkrotonil koenzim A karboksilaza, beta-metilkrotonil koenzim A karboksilaza, beta-metilkrotonil KoA karboksilaza, metilkrotonil-KoA karboksilaza) je enzim sa sistematskim imenom 3-metilkrotonoil-KoA:ugljen-dioksid ligaza (formira ADP).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Metilkrotonoil-KoA karboksilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.4.1.4 | ||||||||
| CAS broj | 9023-95-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Ovaj enzim je biotinilni protein.
Reference уреди
- ^ Knappe, J., Schlegel, H.-G. and Lynen, F. (1961). „Zur biochemischen Funktion des Biotins. I. Die Beteilligung der β-Methyl-crotonyl-Carboxylase an der Bildung von β-Hydroxy-β-methyl-glutaryl-CoA from β-Hydroxy-isovaleryl-CoA”. Biochem. Z. 335: 101—122. PMID 14457200.
- ^ Lynen, F., Knappe, J., Lorch, E., Jütting, G., Ringelmann, E. and Lachance, J.-P. (1961). „Zur biochemischen Funktion des Biotins. II. Reinigung und Wirkungsweise der β-Methyl-crotonyl-Carboxlase”. Biochem. Z. 335: 123—166. PMID 14467590.
- ^ Rilling, H.C. & Coon, M.J. (1960). „The enzymatic isomerization of α-methylvinylacetyl coenzyme A and the specificity of a bacterial α-methylcrotonyl coenzyme A carboxylase”. J. Biol. Chem. 235: 3087—3092. PMID 13741692.
- ^ Vagelos, P. (1971). „Regulation of fatty acid biosynthesis”. Curr. Top. Cell. Regul. 4: 119—166.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Methylcrotonoyl-CoA+carboxylase на US National Library of Medicine Medical Subject Headings (MeSH)
