NADH:ubihinon reduktaza (Na+-transport)
NADH:ubihinon reduktaza (Na+-transport) (EC 1.6.5.8, Na+-translocirajući NADH-hinon reduktaza, (Na+-NQR)) je enzim sa sistematskim imenom NADH:ubihinon oksidoreduktaza (Na+-translocating).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| NADH:ubihinon reduktaza (Na+-transport) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.6.5.8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj flavoprotein sadrži dva kovalentno vezana FMN molekula, jedan nekovalentno vezan FAD, jedan riboflavin, i jedan [2Fe-2S] klaster.
Reference уреди
- ^ Beattie, P., Tan, K., Bourne, R.M., Leach, D., Rich, P.R. and Ward, F.B. (1994). „Cloning and sequencing of four structural genes for the Na+-translocating NADH-ubiquinone oxidoreductase of Vibrio alginolyticus”. FEBS Lett. 356: 333—338. PMID 7805867.
- ^ Nakayama, Y., Hayashi, M. and Unemoto, T. (1998). „Identification of six subunits constituting Na+-translocating NADH-quinone reductase from the marine Vibrio alginolyticus”. FEBS Lett. 422: 240—242. PMID 9490015.
- ^ Bogachev, A.V., Bertsova, Y.V., Barquera, B. and Verkhovsky, M.I. (2001). „Sodium-dependent steps in the redox reactions of the Na+-motive NADH:quinone oxidoreductase from Vibrio harveyi”. Biochemistry. 40: 7318—7323. PMID 11401580.
- ^ Barquera, B., Hellwig, P., Zhou, W., Morgan, J.E., Hase, C.C., Gosink, K.K., Nilges, M., Bruesehoff, P.J., Roth, A., Lancaster, C.R. and Gennis, R.B. (2002). „Purification and characterization of the recombinant Na+-translocating NADH:quinone oxidoreductase from Vibrio cholerae”. Biochemistry. 41: 3781—3789. PMID 11888296.
- ^ Barquera, B., Nilges, M.J., Morgan, J.E., Ramirez-Silva, L., Zhou, W. and Gennis, R.B. (2004). „Mutagenesis study of the 2Fe-2S center and the FAD binding site of the Na+-translocating NADH:ubiquinone oxidoreductase from Vibrio cholerae”. Biochemistry. 43: 12322—12330. PMID 15379571.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- NADH:ubiquinone+reductase+(Na+-transporting) на US National Library of Medicine Medical Subject Headings (MeSH)
