Prolilna oligopeptidaza
Prolilna oligopeptidaza (EC 3.4.21.26, enzim postprolinskog odvajanja, prolinsko specifična endopeptidaza, postprolinska endopeptidaza, prolinska endopeptidaza, endoprolilpeptidaza, prolilna endopeptidaza) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Prolilna oligopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 3.4.21.26 | ||||||||
| CAS broj | 72162-84-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- Hidroliza -Pro- i u manjoj meri -Ala- u oligopeptidima
Ovaj enzim je prisutan u povrću i flavobakterijama.
Reference уреди
- ^ Walter, R. & Yoshimoto, T. (1978). „Postproline cleaving enzyme: kinetic studies of size and stereospecificity of its active site”. Biochemistry. 17: 4139—4144. PMID 708698.
- ^ Nomura, K. (1986). „Specificity of prolyl endopeptidase”. FEBS Lett. 209: 235—237. PMID 3539636.
- ^ Moriyama, A., Nakanishi, M. and Sasaki, M. (1988). „Porcine muscle prolyl endopeptidase and its endogenous substrates”. J. Biochem. (Tokyo). 104: 112—117. PMID 2851585.
- ^ Rennex, D., Hemmings, B.A., Hofsteenge, J. and Stone, S.R. (1991). „cDNA cloning of porcine brain prolyl endopeptidase and identification of the active-site seryl residue”. Biochemistry,. 30: 2195—2203. PMID 1900195.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Prolyl+oligopeptidase на US National Library of Medicine Medical Subject Headings (MeSH)
