Protein-fruktozamin 3-kinaza
Protein-fruktozamin 3-kinaza (EC 2.7.1.171, FN3K, fruktosaminska 3-kinaza) je enzim sa sistematskim imenom ATP:(protein)-N6-D-fruktosil-L-lizin 3-fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Protein-fruktozamin 3-kinaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.7.1.171 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Neenzimatska glikacija je važan faktor u patogenezi diabetičkih komplikacija.
Reference уреди
- ^ Szwergold, B.S., Howell, S. and Beisswenger, P.J. (2001). „Human fructosamine-3-kinase: purification, sequencing, substrate specificity, and evidence of activity in vivo”. Diabetes. 50: 2139—2147. PMID 11522682.
- ^ Delpierre, G., Rider, M.H., Collard, F., Stroobant, V., Vanstapel, F., Santos, H. and Van Schaftingen, E. (2000). „Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase”. Diabetes. 49: 1627—1634. PMID 11016445.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Protein-fructosamine+3-kinase на US National Library of Medicine Medical Subject Headings (MeSH)