Sulfit reduktaza (NADPH)
Sulfit reduktaza (NADPH) (EC 1.8.1.2, sulfit (redukovani nikotinamid adenin dinukleotid fosfat) reduktaza, NADPH-sulfitna reduktaza, NADPH-zavisna sulfitna reduktaza, H2S-NADP oksidoreduktaza, sulfitna reduktaza (NADPH2)) je enzim sa sistematskim imenom vodonik-sulfid:NADP+ oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Sulfit reduktaza (NADPH) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.8.1.2 | ||||||||
| CAS broj | 9029-35-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- vodonik sulfid + 3 NADP+ + 3H2O sulfit + 3 NADPH + 3 H+
Ovaj enzim je gvozdeni flavoprotein (FAD i FMN).
Reference уреди
- ^ Hilz, H., Kittler, M. and Knape, G. (1959). „Die Reduktion von Sulfate in der Hefe”. Biochem. Z. 332: 151—166. PMID 14401842.
- ^ Siegel, L.M., Murphy, M.J. and Kamin, H. (1973). „Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. I. The Escherichia coli hemoflavoprotein: molecular parameters and prosthetic groups”. J. Biol. Chem. 248: 251—264. PMID 4144254.
- ^ Yoshimoto, A. & Sato, R. (1968). „Studies on yeast sulfite reductase. I. Purification and characterization”. Biochim. Biophys. Acta. 153: 555—575. PMID 4384979.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Sulfite+reductase+(NADPH) на US National Library of Medicine Medical Subject Headings (MeSH)
