TRNK pseudouridinska38/39 sintaza
TRNK pseudouridinska38/39 sintaza (EC 5.4.99.45, Deg1, Pus3p, pseudouridin sintaza 3) je enzim sa sistematskim imenom tRNK-uridin38/39 uracil mutaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| TRNK pseudouridinska38/39 sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.4.99.45 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- tRNK uridin38/39 tRNK pseudouridin38/39
Enzim iz Saccharomyces cerevisiae je aktivan samo na uridinu38 i uridinu39.
Reference уреди
- ^ Lecointe, F., Simos, G., Sauer, A., Hurt, E.C., Motorin, Y. and Grosjean, H. (1998). „Characterization of yeast protein Deg1 as pseudouridine synthase (Pus3) catalyzing the formation of Ψ38 and Ψ39 in tRNA anticodon loop”. J. Biol. Chem. 273: 1316—1323. PMID 9430663.
- ^ Chen, J. & Patton, J.R. (2000). „Pseudouridine synthase 3 from mouse modifies the anticodon loop of tRNA”. Biochemistry. 39: 12723—12730. PMID 11027153.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- TRNA+pseudouridine38/39+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
