Triptofan transaminaza
Triptofan transaminaza (EC 2.6.1.27, L-fenilalanin-2-oksoglutaratna aminotransferaza, triptofanska aminotransferaza, 5-hidroksitriptofan-ketoglutarinska transaminaza, hidroksitriptofanska aminotransferaza, L-triptofanska aminotransferaza, L-triptofanska transaminaza) je enzim sa sistematskim imenom L-triptofan:2-oksoglutarat aminotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Triptofan transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.27 | ||||||||
| CAS broj | 9022-98-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Oksaloacetat može da zameni 2-oksoglutarat. On takođe deluje na 5-hidroksitriptofan i u manjoj meri na fenilne aminokiseline.
Reference
уреди- ^ George, H. & Gabay, S. (1968). „Brain aromatic aminotransferase. I. Purification and some properties of pig brain L-phenylalanine-2-oxoglutarate aminotransferase”. Biochim. Biophys. Acta. 167: 555—566. PMID 5722279.
- ^ O'Neil, S.R. & DeMoss, R.D. (1968). „Tryptophan transaminase from Clostridium sporogenes”. Arch. Biochem. Biophys. 127: 361—368. PMID 5697992.
- ^ Tangen, O., Fonnum, F. and Haavaldsen, R. (1965). „Separation and purification of aromatic amino acid transaminases from rat brain”. Biochim. Biophys. Acta. 96: 82—90. PMID 14285270.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Tryptophan+transaminase на US National Library of Medicine Medical Subject Headings (MeSH)
