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| caption = Fosfatidilinozitolna 4-kinaza homo16mer, Human
}}
'''1-Fosfatidilinozitol 4-kinaza''' ({{EC broj-lat|2.7.1.67}}, ''fosfatidilinozitolna kinaza (fosforilacija)'', ''fosfatidilinozitolna 4-kinaza'', ''fosfatidilinozitolna kinaza'', ''tip II fosfatidilinozitolna kinaza'', ''PI kinaza'', ''PI 4-kinaza'') je [[enzim]] sa sistematskim imenom ''ATP:1-fosfatidil-1-{D}--mio-inozitol 4-fosfotransferaza''.<ref>{{cite journal | title = Biosynthesis of diphosphoinositide in brain |author author1= Colodzin, M. and |author2=Kennedy, E.P. |lastauthoramp=yes |journal = J. Biol. Chem. |date = 1965 |volume = 240 |pages = 3771-3780 |pmid = 4284712}}</ref><ref>{{cite journal | title = The phosphatidylinositol kinase of rat brain |author = Kai, M., White, G.L. and Hawthorne, J.N. |journal = Biochem. J. |date = 1966 |volume = 101 |pages = 328-337 |pmid = 4290722}}</ref><ref>{{cite journal | title = Purification and characterization of a phosphatidylinositol kinase from A431 cells |author = Walker, D.H., Dougherty, N. and Pike, L.J. |journal = Biochemistry |date = 1988 |volume = 27 |pages = 6504-6511 |pmid = 2851325}}</ref><ref>{{cite journal | title = Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate |author = Whitman, M., Downes, C.P., Keeler, M., Keller, T. and Cantley, L. |journal = Nature |date = 1988 |volume = 332 |pages = 644-646 |pmid = 2833705}}</ref><ref>{{cite journal | title = A novel family of phosphatidylinositol 4-kinases conserved from yeast to humans |author = Barylko, B., Gerber, S.H., Binns, D.D., Grichine, N., Khvotchev, M., Sudhof, T.C. and Albanesi, J.P. |journal = J. Biol. Chem. |date = 2001 |volume = 276 |pages = 7705-7708 |pmid = 11244087}}</ref> Ovaj enzim [[Катализа|katalizuje]] sledeću [[hemijska reakcija|hemijsku reakciju]]
: [[Аденозин-трифосфат|ATP]] + 1-fosfatidil-1-{D}--mio-inozitol <math>\rightleftharpoons</math> [[Аденозин-дифосфат|ADP]] + 1-fosfatidil-1-{D}--mio-inozitol 4-fosfat
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