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Гастрин — разлика између измена

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Ред 1:
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'''Гастрин''' је [[протеин]]ски [[хормони|хормон]] који синтетишу и секретују Г ћелије ([[гастринска ћелија|гастринске ћелије]]) [[желудац|желуца]]. Дифузног је дејства, индукује секрецију [[Хлороводонична киселина|желудачне киселине]] и стимулише покрете [[желудац|желуца]]. Његово постојање је приви предложио [[1905]]. Британски физиолог Џон Сидни Едкинс,<ref>{{cite journal |author=Edkins JS |title=The chemical mechanism of gastric secretion |journal=J. Physiol. (Lond.) |volume=34 |issue=1-2 |pages=133–44 |date = 13. 3. 1906.|pmid=16992839 |url=http://jp.physoc.org/cgi/reprint/34/1-2/133 | pmc=1465807 }}</ref><ref>{{cite journal |authorvauthors=Modlin IM, Kidd M, Marks IN, Tang LH |title=The pivotal role of John S. Edkins in the discovery of gastrin |journal=World J Surg |volume=21 |issue=2 |pages=226–34 |year=1997 |pmid=8995084 |doi=10.1007/s002689900221}}</ref>. Гастрин су изоловали [[1964]]. Џрегори и Трејси у [[Ливерпул]]у.<ref>{{cite journal |authorvauthors=Gregory RA, Tracy HJ |title=The constitution and properties of two gastrins extracted from hog antral mucosa |journal=Gut |volume=5 |issue= |pages=103–14 |year=1964 |pmid=14159395 |url=http://gut.bmj.com/cgi/reprint/5/2/103 |doi=10.1136/gut.5.2.103 | pmc=1552180}}</ref>
 
== Извори ==
Ред 9:
{{PBB_Further_reading
| citations =
*{{cite journal | authorvauthors=Rozengurt E, Walsh JH |title=Gastrin, CCK, signaling, and cancer |journal=Annu. Rev. Physiol. |volume=63 |issue= |pages= 49–76 |year= 2001 |pmid= 11181948 |doi= 10.1146/annurev.physiol.63.1.49 }}
*{{cite journal | author=Dockray GJ |title=Clinical endocrinology and metabolism. Gastrin |journal=Best Pract. Res. Clin. Endocrinol. Metab. |volume=18 |issue= 4 |pages= 555–68 |year= 2005 |pmid= 15533775 |doi= 10.1016/j.beem.2004.07.003 }}
*{{cite journal | authorauthor1=Anlauf M, |author2=Garbrecht N, |author3=Henopp T, |author4=''et al.'' |title=Sporadic versus hereditary gastrinomas of the duodenum and pancreas: distinct clinico-pathological and epidemiological features |journal=World J. Gastroenterol. |volume=12 |issue= 34 |pages= 5440–6 |year= 2006 |pmid= 17006979 |doi=}}
*{{cite journal | authorauthor1=Polosatov MV, |author2=Klimov PK, |author3=Masevich CG, |author4=''et al.'' |title=Interaction of synthetic human big gastrin with blood proteins of man and animals |journal=Acta hepato-gastroenterologica |volume=26 |issue= 2 |pages= 154–9 |year= 1979 |pmid= 463490 |doi=}}
*{{cite journal | authorvauthors=Fritsch WP, Hausamen TU, Scholten T |title=[Gastrointestinal hormones. I. Hormones of the gastrin group] |journal=Zeitschrift für Gastroenterologie |volume=15 |issue= 4 |pages= 264–76 |year= 1977 |pmid= 871064 |doi=}}
*{{cite journal | authorauthor1=Higashimoto Y, |author2=Himeno S, |author3=Shinomura Y, |author4=''et al.'' |title=Purification and structural determination of urinary NH2-terminal big gastrin fragments |journal=Biochem. Biophys. Res. Commun. |volume=160 |issue= 3 |pages= 1364–70 |year= 1989 |pmid= 2730647| doi=10.1016/S0006-291X(89)80154-8}}
*{{cite journal | authorauthor1=Pauwels S, |author2=Najdovski T, |author3=Dimaline R, |author4=''et al.'' |title=Degradation of human gastrin and CCK by endopeptidase 24.11: differential behaviour of the sulphated and unsulphated peptides |journal=Biochim. Biophys. Acta |volume=996 |issue= 1-2 |pages= 82–8 |year= 1989 |pmid= 2736261 |doi=}}
*{{cite journal | authorvauthors=Lund T, Geurts van Kessel AH, Haun S, Dixon JE |title=The genes for human gastrin and cholecystokinin are located on different chromosomes |journal=Hum. Genet. |volume=73 |issue= 1 |pages= 77–80 |year= 1986 |pmid= 3011648| doi=10.1007/BF00292669}}
*{{cite journal | authorauthor1=Kariya Y, |author2=Kato K, |author3=Hayashizaki Y, |author4=''et al.'' |title=Expression of human gastrin gene in normal and gastrinoma tissues |journal=Gene |volume=50 |issue= 1-3 |pages= 345–52 |year= 1987 |pmid= 3034736 |doi=10.1016/0378-1119(86)90338-0}}
*{{cite journal | authorvauthors=Gregory RA, Tracy HJ, Agarwal KL, Grossman MI |title=Aminoacid constitution of two gastrins isolated from Zollinger-Ellison tumour tissue |journal=Gut |volume=10 |issue= 8 |pages= 603–8 |year= 1969 |pmid= 5822140| doi=10.1136/gut.10.8.603 | pmc=1552899}}
*{{cite journal | authorvauthors=Bentley PH, Kenner GW, Sheppard RC |title=Structures of human gastrins I and II |journal=Nature |volume=209 |issue= 5023 |pages= 583–5 |year= 1967 |pmid= 5921183 |doi=10.1038/209583b0}}
*{{cite journal | authorauthor1=Ito R, |author2=Sato K, |author3=Helmer T, |author4=''et al.'' |title=Structural analysis of the gene encoding human gastrin: the large intron contains an Alu sequence |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=81 |issue= 15 |pages= 4662–6 |year= 1984 |pmid= 6087340| doi=10.1073/pnas.81.15.4662 | pmc=391550}}
*{{cite journal | authorauthor1=Wiborg O, |author2=Berglund L, |author3=Boel E, |author4=''et al.'' |title=Structure of a human gastrin gene |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=81 |issue= 4 |pages= 1067–9 |year= 1984 |pmid= 6322186| doi=10.1073/pnas.81.4.1067 | pmc=344765}}
*{{cite journal | authorauthor1=Kato K, |author2=Hayashizaki Y, |author3=Takahashi Y, |author4=''et al.'' |title=Molecular cloning of the human gastrin gene |journal=Nucleic Acids Res. |volume=11 |issue= 23 |pages= 8197–203 |year= 1984 |pmid= 6324077 |doi=10.1093/nar/11.23.8197 | pmc=326575}}
*{{cite journal | authorauthor1=Boel E, |author2=Vuust J, |author3=Norris F, |author4=''et al.'' |title=Molecular cloning of human gastrin cDNA: evidence for evolution of gastrin by gene duplication |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=80 |issue= 10 |pages= 2866–9 |year= 1983 |pmid= 6574456| doi=10.1073/pnas.80.10.2866 | pmc=393933}}
*{{cite journal | authorauthor1=Kato K, |author2=Himeno S, |author3=Takahashi Y, |author4=''et al.'' |title=Molecular cloning of human gastrin precursor cDNA |journal=Gene |volume=26 |issue= 1 |pages= 53–7 |year= 1984 |pmid= 6689486 |doi=10.1016/0378-1119(83)90035-5}}
*{{cite journal | authorvauthors=Koh TJ, Wang TC |title=Molecular cloning and sequencing of the murine gastrin gene |journal=Biochem. Biophys. Res. Commun. |volume=216 |issue= 1 |pages= 34–41 |year= 1995 |pmid= 7488110 |doi= 10.1006/bbrc.1995.2588 }}
*{{cite journal | authorvauthors=Rehfeld JF, Hansen CP, Johnsen AH |title=Post-poly(Glu) cleavage and degradation modified by O-sulfated tyrosine: a novel post-translational processing mechanism |journal=EMBO J. |volume=14 |issue= 2 |pages= 389–96 |year= 1995 |pmid= 7530658 |doi= | pmc=398093}}
*{{cite journal | authorvauthors=Rehfeld JF, Johnsen AH |title=Identification of gastrin component I as gastrin-71. The largest possible bioactive progastrin product |journal=Eur. J. Biochem. |volume=223 |issue= 3 |pages= 765–73 |year= 1994 |pmid= 8055952| doi=10.1111/j.1432-1033.1994.tb19051.x}}
*{{cite journal | authorvauthors=Varro A, Dockray GJ |title=Post-translational processing of progastrin: inhibition of cleavage, phosphorylation and sulphation by brefeldin A |journal=Biochem. J. |volume=295 (Pt 3) |issue= |pages= 813–9 |year= 1993 |pmid= 8240296 |doi= | pmc=1134634}}
}}
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Преузето из „https://sr.wikipedia.org/wiki/Гастрин”