|
| metabolism =
| elimination_half-life =
| excretion =
<!--Identifiers-->
| StdInChIKey = AQOKCDNYWBIDND-FTOWTWDKSA-N
}}
'''Bimatoprost''' (''Lumigan'') je analog [[prostaglandin]]a. On je [[prolek]] koji se koristi topikalni (u obliku [[kapi za oči]]) za kontrolu progresa [[glaukom]]a i [[okularna hipertenzija|okularne hipertenzije]]. On redukuje [[intraokularni pristisak]] (IOP) putem povećanja odliva fluida iz očiju.<ref name=MedlinePlus>{{cite web | url = http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a602030.html | title = Bimatoprost Ophthalmic | publisher = MedlinePlus | date = 1. 1. 2003. | accessdate = 19. 11. 2007. |archiveurl = http://web.archive.org/web/20071005013222/http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a602030.html |archivedate = 05. 10. 2007.}}</ref> Poznato je da se koristi za produžavanje [[trepavica]].<ref name="WSJ-19-11-2007">{{cite news | title=Drug That Lengthens Eyelashes Sets Off Flutter | url=http://online.wsj.com/article/SB119543055372597359.html | date = 19. 11. 2007. | work = The Wall Street Journal | accessdate = 19. 11. 2007. | first=Rhonda L. | last=Rundle}}</ref> [[FDA]] je odobrila ovaj način primene decembra [[2008]]. Kozmetička formulacija bimatoprosta je u prodaji pod imenom ''Latis''.<ref>{{cite news |url=http://www.businessweek.com/ap/financialnews/D95AF4N81.htm |title=Allergan gets FDA approval for eyelash treatment |agency=[[Associated Press]] |work=BusinessWeek |date = 26. 12. 2008. |accessdate = 26. 12. 2008.}}</ref> Tokom perioda od 2008 - 2011, utvrđeno je da bimatoprost ima sposobnost redukovanja masnog tkiva.<ref name=JapaneseOphSociety>{{cite journal | author vauthors= Park J, Cho HK, Moon JI | title = Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. | journal = Japanese Ophthalmological Society | volume = 55 | issue = 1 | pages = 22–27 | year = 2011 | pmid = 21331688 | doi = 10.1007/s10384-010-0904-z}}</ref><ref name=Orbit>{{cite journal | author vauthors= Jayaprakasam A, Ghazi-Nouri S. | title = Periorbital fat atrophy - an unfamiliar side effect of prostaglandin analogues. | journal = Orbit | volume = 29 | issue = 6 | pages = 357–359 | year = 2010 | pmid = 21158579 | doi = 10.3109/01676830.2010.527028}}</ref><ref name=OphthPlasReconSurg>{{cite journal | author vauthors= Filippopoulos T, Paula JS, Torun N, Hatton MP, Pasquale LR, Grosskreutz CL. | title = Periorbital changes associated with topical bimatoprost. | journal = Ophthalmology Plastic and Reconstructive Surgery | volume = 24 | issue = 4 | pages = 302–307 | year = 2008 | pmid = 18645437 | doi = 10.1097/IOP.0b013e31817d81df}}</ref>
== Reference ==
== Literatura ==
{{refbegin|2}}
* {{cite journal | author vauthors= Chen M, Cheng C, Chen Y, Chou C, Hsu W | title = Effects of bimatoprost 0.03% on ocular hemodynamics in normal tension glaucoma. | journal = J Ocul Pharmacol Ther | volume = 22 | issue = 3 | pages = 188–93 | year = 2006 | pmid = 16808680 | doi = 10.1089/jop.2006.22.188}}
* {{cite journal | author vauthors= Kruse P, Rieck P, Sherif Z, Liekfeld A | title = Cystoid macular edema in a pseudophakic patient after several glaucoma procedures. Is local therapy with bimatoprost the reason? | journal = Klinische Monatsblätter für Augenheilkunde | volume = 223 | issue = 6 | pages = 534–7 | year = 2006 | pmid = 16804825 | doi = 10.1055/s-2005-858992}}
* {{cite journal | author = Steinhäuser S | title = Decreased high-density lipoprotein serum levels associated with topical bimatoprost therapy. | journal = Optometry | volume = 77 | issue = 4 | pages = 177–9 | year = 2006 | pmid = 16567279 | doi = 10.1016/j.optm.2006.02.001}}
* {{cite journal | author vauthors= Park J, Cho HK, Moon JI | title = Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. | journal = Japanese Ophthalmological Society | volume = 55 | issue = 1 | pages = 22–27 | year = 2011 | pmid = 21331688 | doi = 10.1007/s10384-010-0904-z}}
* {{cite journal | author vauthors= Jayaprakasam A, Ghazi-Nouri S. | title = Periorbital fat atrophy - an unfamiliar side effect of prostaglandin analogues. | journal = Orbit | volume = 29 | issue = 6 | pages = 357–359 | year = 2010 | pmid = 21158579 | doi = 10.3109/01676830.2010.527028}}
* {{cite journal | author vauthors= Filippopoulos T, Paula JS, Torun N, Hatton MP, Pasquale LR, Grosskreutz CL. | title = Periorbital changes associated with topical bimatoprost. | journal = Ophthalmology Plastic and Reconstructive Surgery | volume = 24 | issue = 4 | pages = 302–307 | year = 2008 | pmid = 18645437 | doi = 10.1097/IOP.0b013e31817d81df}}
{{refend}}
== Spoljašnje veze ==
| 