Википедија

TRIO (gen) — разлика између измена

Интерактиван преглед историје
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ВизуелноВикитекст
м . using AWB
Ред 1:
{{PBB|geneid=7204}}
'''Protein trofunkcionog domena''' ({{jez-eng-lat|Triple functional domain protein}}) je [[protein]] koji je kod ljudi kodiran ''TRIO'' [[gen]]om.<ref name="pmid8643598">{{cite journal | author vauthors= Debant A, Serra-Pages C, Seipel K, O'Brien S, Tang M, Park SH, Streuli M | title = The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains | journal = Proc Natl Acad Sci U S A | volume = 93 | issue = 11 | pages = 5466–71 | year = 1996 | month = July | pmid = 8643598 | pmc = 39269 | doi =10.1073/pnas.93.11.5466 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TRIO triple functional domain (PTPRF interacting)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7204| accessdate = }}</ref>
 
==Interakcije==
TRIO (gen) formira [[Protein-protein interakcija|interakcije]] sa [[filamin]]om<ref name=pmid11146652>{{cite journal |last=Bellanger |first=J M |authorlink= |coauthors=Astier C, Sardet C, Ohta Y, Stossel T P, Debant A |year=2000|month=December |title=The Rac1- and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actin |journal=Nat. Cell Biol. |volume=2 |issue=12 |pages=888–92 |publisher= |location = ENGLAND| issn = 1465-7392| pmid = 11146652 |doi = 10.1038/35046533 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> i -{[[RHOA]]}-.<ref name=pmid10948190>{{cite journal |last=Medley |first=Q G |authorlink= |coauthors=Serra-Pagès C, Iannotti E, Seipel K, Tang M, O'Brien S P, Streuli M |year=2000|month=November |title=The trio guanine nucleotide exchange factor is a RhoA target. Binding of RhoA to the trio immunoglobulin-like domain |journal=J. Biol. Chem. |volume=275 |issue=46 |pages=36116–23 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 10948190 |doi = 10.1074/jbc.M003775200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>
 
==Reference==
Ред 20:
*{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 | author-separator=, | author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }}
*{{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 | author-separator=, | author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki }}
*{{cite journal | authorvauthors=Skowronek KR, Guo F, Zheng Y, Nassar N |title=The C-terminal basic tail of RhoG assists the guanine nucleotide exchange factor trio in binding to phospholipids |journal=J. Biol. Chem. |volume=279 |issue= 36 |pages= 37895–907 |year= 2004 |pmid= 15199069 |doi= 10.1074/jbc.M312677200 }}
*{{cite journal | author=Zheng M |title=TRIO Amplification and Abundant mRNA Expression Is Associated with Invasive Tumor Growth and Rapid Tumor Cell Proliferation in Urinary Bladder Cancer |journal=Am. J. Pathol. |volume=165 |issue= 1 |pages= 63–9 |year= 2004 |pmid= 15215162 |doi= 10.1016/S0002-9440(10)63275-0| pmc=1618551 | author-separator=, | author2=Simon R | author3=Mirlacher M | display-authors=3 | last4=Maurer | first4=R | last5=Gasser | first5=T | last6=Forster | first6=T | last7=Diener | first7=PA | last8=Mihatsch | first8=MJ | last9=Sauter | first9=G }}
*{{cite journal | author=Yoshizuka N |title=An alternative transcript derived from the trio locus encodes a guanosine nucleotide exchange factor with mouse cell-transforming potential |journal=J. Biol. Chem. |volume=279 |issue= 42 |pages= 43998–4004 |year= 2004 |pmid= 15308664 |doi= 10.1074/jbc.M406082200 | author-separator=, | author2=Moriuchi R | author3=Mori T | display-authors=3 | last4=Yamada | first4=K | last5=Hasegawa | first5=S | last6=Maeda | first6=T | last7=Shimada | first7=T | last8=Yamada | first8=Y | last9=Kamihira | first9=S }}
Ред 28:
*{{cite journal | author=Adamowicz M |title=Frequent amplifications and abundant expression of TRIO, NKD2, and IRX2 in soft tissue sarcomas |journal=Genes Chromosomes Cancer |volume=45 |issue= 9 |pages= 829–38 |year= 2006 |pmid= 16752383 |doi= 10.1002/gcc.20343 | author-separator=, | author2=Radlwimmer B | author3=Rieker RJ | display-authors=3 | last4=Mertens | first4=Daniel | last5=Schwarzbach | first5=Matthias | last6=Schraml | first6=Peter | last7=Benner | first7=Axel | last8=Lichter | first8=Peter | last9=Mechtersheimer | first9=Gunhild }}
*{{cite journal | author=Olsen JV |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 | author-separator=, | author2=Blagoev B | author3=Gnad F | display-authors=3 | last4=Macek | first4=Boris | last5=Kumar | first5=Chanchal | last6=Mortensen | first6=Peter | last7=Mann | first7=Matthias }}
*{{cite journal | authorvauthors=Chhatriwala MK, Betts L, Worthylake DK, Sondek J |title=The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation |journal=J. Mol. Biol. |volume=368 |issue= 5 |pages= 1307–20 |year= 2007 |pmid= 17391702 |doi= 10.1016/j.jmb.2007.02.060 | pmc=1890047 }}
*{{cite journal | author=Rojas RJ |title=Gαq Directly Activates p63RhoGEF and Trio via a Conserved Extension of the Dbl Homology-associated Pleckstrin Homology Domain |journal=J. Biol. Chem. |volume=282 |issue= 40 |pages= 29201–10 |year= 2007 |pmid= 17606614 |doi= 10.1074/jbc.M703458200 | pmc=2655113 | author-separator=, | author2=Yohe ME | author3=Gershburg S | display-authors=3 | last4=Kawano | first4=T. | last5=Kozasa | first5=T. | last6=Sondek | first6=J. }}
}}
Преузето из „https://sr.wikipedia.org/wiki/TRIO_(gen)”