Supstanca P — разлика између измена

U [[neuronauka|neuronauci]] '''supstanca P''' (SP) je [[neuropeptid]]: undekapeptid koji funkcioniše kao [[neurotransmiter]] i [[neuromodulator]].<ref name="pmid11378438">{{cite journal |vauthors=Harrison S, Geppetti P | title = Substance p | journal = The International Journal of Biochemistry & Cell Biology | volume = 33 | issue = 6 | pages = 555–76 | year = 2001 | pmid = 11378438 | doi = 10.1016/S1357-2725(01)00031-0 | url = }}</ref><ref name="pmid14754378">{{cite journal | vauthors = Datar P, Srivastava S, Coutinho E, Govil G | title = Substance P: structure, function, and therapeutics | journal = Current topics in medicinal chemistry | volume = 4 | issue = 1 | pages = 75–103 | year = 2004 | pmid = 14754378 | doi = 10.2174/1568026043451636 | url = http://www.bentham-direct.org/pages/content.php?CTMC/2004/00000004/00000001/0009R.SGM | access-date = 19. 09. 2018 | archive-url = https://web.archive.org/web/20090817115536/http://www.bentham-direct.org/pages/content.php?CTMC%2F2004%2F00000004%2F00000001%2F0009R.SGM | archive-date = 17. 08. 2009 | dead-url -status= yesdead | df = }}</ref> Ovaj molekul pripada familiji [[tahikinin]]skih neuropeptida. Supstanca P i njen blisko srodni neuropeptid [[neurokinin A]] (NKA) nastaju iz poliproteinskog prekurzora nakon diferencijalnog splajsovanja gena preprotahikinina A. Aminokiselinska sekvenca supstance P je<ref name="pmid">{{cite journal |vauthors=Chang MM, Leeman SE, Niall HD | title = Amino-acid sequence of substance P | journal = Nature: New Biology | volume = 232 | issue = 29 | pages = 86–7 | year = 1971 | pmid = | doi = | url = | issn = | accessdate = 31. 03. 2011.}}</ref><ref name="pmid4613983">{{cite journal |vauthors=Leeman SE, Mroz EA | title = Substance P | journal = Life Sciences | volume = 15 | issue = 12 | pages = 2033–44 | year = 1974 | pmid = 4613983 | doi = | url = | issn = | accessdate = 31. 03. 2011.}}</ref>: