Fosforilacija — разлика између измена
Садржај обрисан Садржај додат
мНема описа измене |
мНема описа измене |
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Ред 7:
=== Istorija ===
Foebus A. Leven sa ''Rokfelerovog instituta za medicinska istraživanja'' je [[1906]]. identifikovao fosfat u proteinu [[vitelin]] (fosvitin),<ref name = "Levene_1906">{{cite journal | title = The cleavage products of vitellin | journal = J. Biol. Chem. | volume = 2 | issue = 1 | pages = 127–133 | year = 1906 | month = | doi = | url = http://www.jbc.org/cgi/reprint/2/1/127.pdf | author1 = Levene PA | author2 = Alsberg CL | author-separator = , }}</ref> i do [[1933]] je detektovao fosfoserin u [[kazein]]u, sa Fricom Lipmanom.<ref name = "Lipmann_1932">{{cite journal | title = Serinephosphoric acid obtained on hydrolysis of vitellinic acid | journal = J. Biol. Chem. | volume = 98 | issue = 1 | pages = 109–114 | year = 1932 | month = October| doi = | url = http://www.jbc.org/cgi/reprint/98/1/109.pdf | author1 = Lipmann FA | author2 = Levene PA | author-separator = , }}</ref> Nakon toga je prošlo 20 godina pre nego što je Eugen P. Kenedi opisao prvu ‘enzimatsku fosforilaciju proteina’.<ref name="pmid13221602">{{cite journal | title = The enzymatic phosphorylation of proteins | journal = J. Biol. Chem. | volume = 211 | issue = 2 | pages = 969–80 | year = 1954 | month = December | pmid = 13221602 | doi = | url = http://www.jbc.org/cgi/reprint/211/2/969.pdf | issn = | author1 = Burnett G | author2 = Kennedy EP | author-separator = , }}</ref>
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