LIG4 — разлика између измена
Садржај обрисан Садржај додат
мНема описа измене |
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Ред 4:
Defekti ovog gena uzrokuju [[LIG4 sindrom]]. Lig4 homolog u kvascu je -{Dnl4}-.
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-{Lig4}- formira kompleks sa -{[[XRCC4]]}-,<ref name=pmid17567543>{{cite journal |author=Deshpande Rajashree A, Wilson Thomas E |year=[[2007]]|month=Oct. |title=Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4 |journal=DNA Repair (Amst.) |volume=6 |issue=10 |pages=1507–16 |publisher= |location = Netherlands| issn = 1568-7864| pmid = 17567543 |doi = 10.1016/j.dnarep.2007.04.014 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=2064958 }}</ref><ref name=pmid11702069>{{cite journal |author=Sibanda B L, Critchlow S E, Begun J, Pei X Y, Jackson S P, Blundell T L, Pellegrini L |year=[[2001]]|month=Dec. |title=Crystal structure of an Xrcc4-DNA ligase IV complex |journal=Nat. Struct. Biol. |volume=8 |issue=12 |pages=1015–9 |publisher= |location = United States| issn = 1072-8368| pmid = 11702069 |doi = 10.1038/nsb725 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> i dalje interaguje sa DNK zavisnom proteinskom kinazom (-{''DNA-PK''}-) i -{[[XLF (protein)|XLF/Cernunnos]]}-.
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