Википедија

Sunepitron — разлика између измена

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ВизуелноВикитекст
м .
м ispravke; козметичке измене
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<!--Clinical data-->
| tradename =
| pregnancy_category =
| legal_status = Nije kontrolisana supstanca
| routes_of_administration = Oralno
 
<!--Pharmacokinetic data-->
| bioavailability =
| metabolism =
| elimination_half-life =
| excretion =
 
<!--Identifiers-->
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| CAS_number = 148408-65-5
| ATC_prefix = none
| ATC_suffix =
| PubChem = 9799246
| IUPHAR_ligand =
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| molecular_weight = 329,40 -{g/mol}-
| smiles = O=C1N(C(=O)CC1)CC4CCC3N(CCN(c2ncccn2)C3)C4
| InChI =
| InChIKey =
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI =
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}}
 
'''Sunepitron''' (-{''CP-93,393''}-) je kombinovani [[agonist (farmakologija)|agonist]] [[5-HT1A receptor|-{5-HT<sub>1A</sub>}- receptora]] i [[antagonist (farmakologija)|antagonist]] [[Alfa-2 adrenergički receptor|α<sub>2</sub>-adrenergičkog receptora]].<ref name="pmid18438295">{{cite journal | author = Goodnick PJ | title = Psychopharmacology of depression in the next millennium | journal = CNS Spectrums | volume = 4 | issue = 7 | pages = 21–35 | year = 1999 | month = July | pmid = 18438295 | doi = | url = }}</ref><ref name="isbn0-521-64615-4">{{cite book | author = Stahl, S. M. | title = Essential psychopharmacology: neuroscientific basis and practical application | publisher = Cambridge University Press | location = Cambridge, UK | year = 2000 | pages = | isbn = 0-521-64615-4 | oclc = | doi = | url = http://books.google.com/books?id=ICztBCFFRqEC&lpg=PA306&pg=PA265#v=onepage&q=&f=false}}</ref> On je bio u razvoju za tretiranje [[klinička depresija|depresije]] i [[anksioznost|anksioznosti]]i.<ref name="isbn0-7373-0417-0">{{cite book | author = Kaplan, Eliot F.; Turkington, Carol | title = Making the antidepressant decision: how to choose the right treatment option for you and your loved ones | publisher = Contemporary Books | location = Chicago, Ill | year = 2001 | pages = | isbn = 0-7373-0417-0 | oclc = | doi = | url = http://books.google.com/books?id=qVtvcsUy2U8C&lpg=PA218&pg=PA218#v=onepage&q=&f=false}}</ref> Dospeo je do faze III [[kliničko ispitivanje|kliničkih ispitivanja]] pre nego što je razvoj prekinut.<ref name="isbn0-521-64615-4">{{cite book | author = Stahl, S. M. | title = Essential psychopharmacology: neuroscientific basis and practical application | publisher = Cambridge University Press | location = Cambridge, UK | year = 2000 | pages = | isbn = 0-521-64615-4 | oclc = | doi = | url = http://books.google.com/books?id=ICztBCFFRqEC&lpg=PA306&pg=PA265#v=onepage&q=&f=false}}</ref><ref name="isbn0-7373-0417-0">{{cite book | author = Kaplan, Eliot F.; Turkington, Carol | title = Making the antidepressant decision: how to choose the right treatment option for you and your loved ones | publisher = Contemporary Books | location = Chicago, Ill | year = 2001 | pages = | isbn = 0-7373-0417-0 | oclc = | doi = | url = http://books.google.com/books?id=qVtvcsUy2U8C&lpg=PA218&pg=PA218#v=onepage&q=&f=false}}</ref>
 
== Sinteza ==
Jedan od mogućih sintetičkih puteva je:<ref>-{G.N. Bright, K.A. Desai, {{US Patent|5,122,525}} (1992).}-</ref>
:[[FileДатотека:Sunepitron synth.png|500px]]
 
== Vidi još ==
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== Reference ==
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{{Antidepresivi-lat}}
Преузето из „https://sr.wikipedia.org/wiki/Sunepitron”