Peptidni hormon — разлика између измена
Садржај обрисан Садржај додат
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Ред 5:
Prohormoni često sadrže suvišne aminokiseline, koje su bile neophodne za usmeravanje [[Savijanje (hemija)|savijanja]] hormonskog molekula u njegovu aktivnu konformaciju, ali nakon toga nemaju funkciju. Specifične [[endopeptidaza|endopeptidaze]] u ćeliji odsecaju prohormon neposredno pre njegovog oslobađanja u [[Cirkulatorni sistem čoveka|krvotok]], generišući krajnju formu hormona. Zreli peptidni hormoni zatim difuzuju putem krvi do svih ćelija u telu, gde oni interaguju sa specifičnim [[receptor (biohemija)|receptorima]] na površni njihovih ciljnih ćelija. Neki peptidni/proteinski hormoni ([[angiotenzin|angiotenzin II]], [[osnovni faktor rasta fibroblasta]]-2, [[paratiroidnom hormonu-srodan protein]]) takođe interaguju sa [[intracelularni receptor|intracelularnim receptorima]] lociranim u [[citoplazma|citoplazmi]] ili jedru putem [[intrakrini|intrakrinog]] mehanizma.<ref name="isbn1-4051-3017-2">{{Cite book | author = Rogol, Alan David; Kraemer, William J. | authorlink = | editor = | others = | title = The endocrine system in sports and exercise | edition = | language = | publisher = Blackwell Pub | location = Cambridge, MA | year = 2005 | origyear = | pages = | quote = | id = ISBN 1-4051-3017-2 | oclc = | doi = | url =http://books.google.com/books?id=TlC5Hfl04sMC | accessdate = }}</ref>
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== Литература ==
* {{Cite book |ref= harv|author = Siddle, K. | authorlink = | editor = | others = | title = Peptide hormone secretion: a practical approach | edition = | language = | publisher = IRL Press at Oxford University Press | location = Oxford | year = 1990 | origyear = | pages = | quote = | id = ISBN 0-19-963073-9 | oclc = | doi = | url =http://books.google.com/books?id=hrp1AAAACAAJ | accessdate =
* {{Cite book |ref= harv|author = Siddle, K. | authorlink = | editor = | others = | title = Peptide hormone secretion: a practical approach | edition = | language = | publisher = IRL Press at Oxford University Press | location = Oxford | year = 1990 | origyear = | pages = | quote = | id = ISBN 0-19-963068-2 | oclc = | doi = | url =http://books.google.com/books?id=QmNrJgAACAAJ&dq=peptide+hormone | accessdate =
* {{Cite book |ref= harv|author = Rogol, Alan David; Kraemer, William J. | authorlink = | editor = | others = | title = The endocrine system in sports and exercise | edition = | language = | publisher = Blackwell Pub | location = Cambridge, MA | year = 2005 | origyear = | pages = | quote = | id = ISBN 1-4051-3017-2 | oclc = | doi = | url =http://books.google.com/books?id=TlC5Hfl04sMC | accessdate =
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