'''Beta blokatori''' (''β-blokatori'', beta-adrenergički blokirajući agensi, beta-adrenergički antagonisti, antagonisti beta-adrenoreceptora, beta antagonisti) su klasa [[lek]]ova koji se koriste za različite indikacije. Oni se pogotovo važni u kontroli [[srčana aritmija|srčanih aritmija]], kardiozaštiti nakon [[Срчани удар|srčanog udara]]<ref name="pmid10381708">{{cite journal |author=Freemantle N, Cleland J, Young P, Mason J, Harrison J |title=beta Blockade after myocardial infarction: systematic review and meta regression analysis |journal=BMJ |volume=318 |issue=7200 |pages=1730–7 |year=1999 |month=June |pmid=10381708 |pmc=31101 |doi= |url=http://bmj.com/cgi/pmidlookup?view=long&pmid=10381708 |accessdate =2010-09- 06. 09. 2010.}}</ref> i tretmanu [[hipertenzija|hipertenzije]].<ref name="pmid20692524">{{cite journal |author=Cruickshank JM |title=Beta blockers in hypertension |journal=Lancet |volume=376 |issue=9739 |pages=415; author reply 415–6 |year=2010 |month=August |pmid=20692524 |doi=10.1016/S0140-6736(10)61217-2 |url=http://linkinghub.elsevier.com/retrieve/pii/S0140-6736(10)61217-2 |accessdate =2010-09- 06. 09. 2010.}}</ref> Kao [[antagonist (farmakologija)|antagonisti]] [[adrenergički receptor|beta adrenergičkog receptora]] oni umanjuju dejstvo [[epinefrin]]a (adrenalina) i drugih hormona stresa. Prvi beta blokator, dihloroizoproterenol, je sintetisan [[1958]].<ref name="urlFifty years of beta-blockers: a revolution in CV pharmacotherapy">{{cite web| url = http://www.cardiologytoday.com/view.aspx?rid=33841| title = Fifty years of beta-blockers: a revolution in CV pharmacotherapy| author = William H. Frishman| authorlink = http://www.nymc.edu/People/William.H.Frishman/index.html| date = 2008-12| publisher = Cardiology Today| accessdate = 2010-09-06. 09. 2010.}}</ref> [[Džejms Blejk (farmakolog)|Džejms V. Blejk]] je [[1962]].<ref name="urlSir James Black inventor of beta-blockers passes away">{{cite web |url=http://www.news-medical.net/news/20100323/Sir-James-Black-inventor-of-beta-blockers-passes-away.aspx |title=Sir James Black inventor of beta-blockers passes away |format= |work= |accessdate =2010-09- 06. 09. 2010.}}</ref> pronašao prve klinički značajne beta blokatore - [[propranolol]] i [[pronetalol]]. To je revolucioniralo medicinski tretman [[angina pektoris|angine pektoris]]<ref name="pmid10378820">{{cite journal |author=van der Vring JA |title=Combination of calcium channel blockers and beta blockers for patients with exercise-induced angina pectoris: a double-blind parallel-group comparison of different classes of calcium channel blockers. The Netherlands Working Group on Cardiovascular Research (WCN) |journal=Angiology |volume=50 |issue=6 |pages=447–454 |year=1999 |month=June |pmid=10378820 |doi= 10.1177/000331979905000602|url=http://ang.sagepub.com/cgi/pmidlookup?view=long&pmid=10378820 |accessdate =2010-09- 06. 09. 2010. |author-separator=, |display-authors=3}}</ref> i mnogi to smatraju jednim od najvažnijih doprinosa kliničkoj medicini i [[farmakologija|farmakologiji]] u [[20. vek|20. veku]]u.<ref name="pmid9456487">{{cite journal| author = Stapleton MP| title = Sir James Black and propranolol. The role of the basic sciences in the history of cardiovascular pharmacology| journal = Texas Heart Institute Journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital| volume = 24| issue = 4| pages = 336–42| year = 1997| pmid = 9456487| pmc = 325477}}</ref>
== Reference ==
{{Reflist|2}}
== Vidi još ==
* [[Alfa blokator]]
== Spoljašnje veze ==
* [http://musiciansway.com/blog/?p=1656 -{Musicians and beta-blockers}-]
* [http://www.nytimes.com/2004/10/17/arts/music/17tind.html -{Better Playing Through Chemistry}-]
