1-pirolidin dehidrogenaza
1-pirolidin dehidrogenaza (EC 1.5.1.35, gama-aminobutiraldehidna dehidrogenaza, ABALDH, YdcW) je enzim sa sistematskim imenom 1-pirolidin:NAD+ oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 1-pirolidin dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.1.35 | ||||||||
| CAS broj | 9054-82-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 1-pirolidin + NAD+ + 2H2O 4-aminobutanoat + NADH + 2 H+
1-pirolidin se spontano formira iz 4-aminobutanala, posredstvom enzima EC 2.6.1.82, putrescin aminotransferaze. Ovaj enzim formira deo puta argininskog katabolizma.
Reference уреди
- ^ Prieto-Santos, M.I., Martin-Checa, J., Balaña-Fouce, R. and Garrido-Pertierra, A. (1986). „A pathway for putrescine catabolism in Escherichia coli”. Biochim. Biophys. Acta. 880: 242—244. PMID 3510672.
- ^ Prieto, M.I., Martin, J., Balaña-Fouce, R. and Garrido-Pertierra, A. (1987). „Properties of γ-aminobutyraldehyde dehydrogenase from Escherichia coli”. Biochimie. 69: 1161—1168. PMID 3129020.
- ^ Samsonova, N.N., Smirnov, S.V., Novikova, A.E. and Ptitsyn, L.R. (2005). „Identification of Escherichia coli K12 YdcW protein as a γ-aminobutyraldehyde dehydrogenase”. FEBS Lett. 579: 4107—4112. PMID 16023116.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- 1-pyrroline+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
