Glukan 1,4-a-glukozidaza
Glukan 1,4-a-glukozidaza (EC 3.2.1.3, glukoamilaza, amiloglukozidaza, gama-amilaza, lizozomalna alfa-glukozidaza, kiselinska maltaza, ekso-1,4-alfa-glukozidaza, glukozna amilaza, gama-1,4-glukanska glukohidrolaza, kiselinska maltaza, 1,4-alfa-D-glukanska glukohidrolaza) je enzim sa sistematskim imenom 4-alfa-D-glukan glukohidrolaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glukan 1,4-a-glukozidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.2.1.3 | ||||||||
| CAS broj | 9032-08-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- hidroliza terminalnih (1->4)-vezanih alfa-D-glukoznih ostataka sukcesivno sa neredukujućih krajeva lanaca uz oslobađanje beta-D-glukoza
Većina formi ovog enzima brzo hidrolizuje 1,6-alfa-D-glukozidne veze.
Reference уреди
- ^ French, D. & Knapp, D.W. (1950). „The maltase of Clostridium acetobutylicum”. J. Biol. Chem. 187: 463—471. PMID 14803428.
- ^ Illingworth Brown, B. & Brown, D.H. (1965). „The subcellular distribution of enzymes in type II glycogenosis and the occurrence of an oligo-α-1,4-glucan glucohydrolase in human tissues”. Biochim. Biophys. Acta. 110: 124—133. PMID 4286143.
- ^ Jeffrey, P.L., Brown, D.H. and Brown, B.I. (1970). „Studies of lysosomal α-glucosidase. I. Purification and properties of the rat liver enzyme”. Biochemistry. 9: 1403—1415. PMID 4313883.
- ^ Kelly, J.J. & Alpers, D.H. (1973). „Properties of human intestinal glucoamylase”. Biochim. Biophys. Acta. 315: 113—122. PMID 4743896.
- ^ Miller, K.D. & Copeland, W.H. (1956). „A blood trans-α-glucosylase”. Biochim. Biophys. Acta. 22: 193—194. PMID 13373867.
- ^ Tsujisaka, Y., Fukimoto, J. and Yamamoto, T. (1958). „Specificity of crystalline saccharogenic amylase of moulds”. Nature. 181: 770—771. PMID 13517301.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Glucan+1,4-alpha-glucosidase на US National Library of Medicine Medical Subject Headings (MeSH)
