(-)-Izopiperitenone reduktaza
(преусмерено са (+)-cis-izopulegon:NADP+ oksidoreduktaza)
(-)-Izopiperitenone reduktaza (EC 1.3.1.82, (-)-izopiperitenonska reduktaza) je enzim sa sistematskim imenom (+)-cis-izopulegon:NADP+ oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| (-)-Izopiperitenone reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.1.82 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (+)-cis-izopulegon + NADP+ (-)-izopiperitenon + NADPH + H+
Ova reakcija teče u reverznom smeru. Enzim učestvuje u putu mentolne biosinteze kod Mentha biljki. (+)-pulegon, (+)-cis-isopulegon i (-)-menton nisu supstrati.
Reference уреди
- ^ Croteau, R. & Venkatachalam, K.V. (1986). „Metabolism of monoterpenes: demonstration that (+)-cis-isopulegone, not piperitenone, is the key intermediate in the conversion of (-)-isopiperitenone to (+)-pulegone in peppermint (Mentha piperita)”. Arch. Biochem. Biophys. 249: 306—315. PMID 3755881.
- ^ Ringer, K.L.; cConkey, M.E.; Davis, E.M.; Rushing, G.W.; Croteau, R. (2003). „Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint”. Arch. Biochem. Biophys. 418: 80—92. PMID 13679086.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- (-)-isopiperitenone+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
