(Izocitrat dehidrogenaza (NADP+)) kinaza
(izocitrat dehidrogenaza (NADP+)) kinaza (EC 2.7.11.5, (izocitratna dehidrogenaza (NADP+)) kinaza, ICDH kinaza/fosfataza, IDH kinaza, IDH kinaza/fosfataza, IDH-K/P, IDHK/P, izocitrat dehidrogenaza kinaza (fosforilacija), izocitrat dehidrogenaza kinaza/fosfataza, STK3) je enzim sa sistematskim imenom ATP:(izocitrat dehidrogenaza (NADP+)) fosfotransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| (izocitrat dehidrogenaza (NADP+)) kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.11.5 | ||||||||
| CAS broj | 83682-93-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Ovaj enzim nema aktivirajuće jedinjenje, ali je specifičan za svoj supstrat.
Reference уреди
- ^ Wang, J.Y.J. & Koshland, D.E., Jr. (1982). „The reversible phosphorylation of isocitrate dehydrogenase of Salmonella typhimurium”. Arch. Biochem. Biophys. 218: 59—67. PMID 6756316.
- ^ Miller, S.P., Karschnia, E.J., Ikeda, T.P. and LaPorte, D.C. (1996). „Isocitrate dehydrogenase kinase/phosphatase. Kinetic characteristics of the wild-type and two mutant proteins”. J. Biol. Chem. 271: 19124—19128. PMID 8702587.
- ^ Singh, S.K., Matsuno, K., LaPorte, D.C. and Banaszak, L.J. (2001). „Crystal structure of Bacillus subtilis isocitrate dehydrogenase at 1.55 Å. Insights into the nature of substrate specificity exhibited by Escherichia coli isocitrate dehydrogenase kinase/phosphatase”. J. Biol. Chem. 276: 26154—26163. PMID 11290745.
- ^ Oudot, C., Cortay, J.C., Blanchet, C., Laporte, D.C., Di Pietro, A., Cozzone, A.J. and Jault, J.M. (2001). „T'he "catalytic" triad of isocitrate dehydrogenase kinase/phosphatase from E. coli and its relationship with that found in eukaryotic protein kinases”. Biochemistry. 40: 3047—3055. PMID 11258918.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- (isocitrate+dehydrogenase+(NADP+))+kinase на US National Library of Medicine Medical Subject Headings (MeSH)
