(R)-limonen 6-monooksigenaza
(R)-limonen 6-monooksigenaza (EC 1.14.13.80, (+)-limonen-6-hidroksilaza, (+)-limonenska 6-monooksigenaza) je enzim sa sistematskim imenom (R)-limonen,NADPH:kiseonik oksidoreduktaza (6-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| (R)-limonen 6-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.80 | ||||||||
| CAS broj | 221461-49-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- (R)-limonen + NADPH + H+ + O2 (+)-trans-karveol + NADP+ + H2O
Reakcija je stereospecifična sa 95% prinosa (+)-trans-karveola iz (R)-limonena.
Reference уреди
- ^ Bouwmeester, H.J., Gershenzon, J., Konings, M.C.J.M. and Croteau, R. (1998). „Biosynthesis of the monoterpenes limonene and carvone in the fruit of caraway. I. Demonstration of enzyme activities and their changes with development”. Plant Physiol. 117: 901—912. PMID 9662532.
- ^ Bouwmeester, H.J., Konings, M.C.J.M., Gershenzon, J., Karp, F. and Croteau, R. (1999). „Cytochrome P-450 dependent (+)-limonene-6-hydroxylation in fruits of caraway (Carum Carvi)”. Phytochemistry. 50: 243—248.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- (R)-limonene+6-monooxygenase на US National Library of Medicine Medical Subject Headings (MeSH)
