2-Ketoarginin metiltransferaza
2-Ketoarginin metiltransferaza (EC 2.1.1.243, mrsA (gen)) je enzim sa sistematskim imenom S-adenozil-L-metionin:5-karbamimidamido-2-oksopentanoat S-metiltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
2-Ketoarginin metiltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.1.1.243 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- S-adenozil-L-metionin + 5-guanidino-2-oksopentanoat S-adenozil-L-homocistein + 5-guanidino-3-metil-2-oksopentanoat
Ovaj enzim učestvuje u produkciji retke aminokiseline 3-metilarginina, koju koristi epifitna bakterija Pseudomonas syringae pv. Syringae kao antibiotik protiv srodnih patogenih vrsta Pseudomonas syringae pv. Glicina.
Reference
уреди- ^ Braun, S.D., Hofmann, J., Wensing, A., Ullrich, M.S., Weingart, H., Völksch, B. and Spiteller, D. (2010). „Identification of the biosynthetic gene cluster for 3-methylarginine, a toxin produced by Pseudomonas syringae' pv. syringae 22d/93”. Appl. Environ. Microbiol. 76: 2500—2508. PMID 20190091.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- 2-ketoarginine+methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)