Cinanserin

Cinanserin
IUPAC ime
	(2E)-N-(2-{[3-(dimetilamino)propil]tio}fenil)-3-fenilakrilamid
Identifikatori
CAS broj	1166-34-3
ATC kod	none
PubChem	CID 5475158
ChemSpider	4584027
UNII	KI6J9OY7A3
Hemijski podaci
Formula	C20H24N2OS
Molarna masa	340,482 g/mol
	SMILES CN(C)CCCSC1=CC=CC=C1NC(=O)\C=C\C2=CC=CC=C2; ;
	InChI InChI=1S/C20H24N2OS/c1-22(2)15-8-16-24-19-12-7-6-11-18(19)21-20(23)14-13-17-9-4-3-5-10-17/h3-7,9-14H,8,15-16H2,1-2H3,(H,21,23)/b14-13+ ; Key:RSUVYMGADVXGOU-BUHFOSPRSA-N ;

Cinanserin je antagonist 5-HT_2A i 5-HT_2C receptora koji je otkriven tokom 1960-tih.^[1]

Preparat cinanserina je efektivan protiv atipične pneumonije (SARS).^[2]

Vidi još уреди

^ Neuman RS, Zebrowska G (1992). „Serotonin (5-HT2) receptor mediated enhancement of cortical unit activity”. Canadian Journal of Physiology and Pharmacology. 70 (12): 1604—9. PMID 1301238.
^ Lili Chen; Chunshan Gui; Xiaomin Luo; Qingang Yang; Stephan Günther; Elke Scandella; Christian Drosten; Donglu Bai; Xichang He; Burkhard Ludewig; Jing Chen; Haibin Luo; Yiming Yang; Yifu Yang; Jianping Zou; Volker Thiel; Kaixian Chen; Jianhua Shen; Xu Shen; Hualiang Jiang (2005). „Cinanserin Is an Inhibitor of the 3C-Like Proteinase of Severe Acute Respiratory Syndrome Coronavirus and Strongly Reduces Virus Replication In Vitro”. J. Virol. 79: 7095—7103. Архивирано из оригинала 11. 08. 2020. г. Приступљено 16. 11. 2012.