Histon-lizin N-metiltransferaza
Histon-lizin N-metiltransferaza (EC 2.1.1.43, proteinska metilaza III, proteinska metilaza 3, proteinska (lizin) metiltransferaza, proteinska metiltransferaza II, protein-lizinska N-metiltransferaza, histon H1-specifični S-adenozilmetionin:protein-lizin N-metiltransferaza, S-adenozil-L-metionin:histon-L-lizin 6-N-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:histon-L-lizin N6-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Histon-lizin N-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.43 | ||||||||
| CAS broj | 2613530 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- S-adenozil-L-metionin + histon L-lizin S-adenozil-L-homocistein + histon N6-metil-L-lizin
Ovaj enzim pripada grup metilacionih proteina.
Reference уреди
- ^ Paik, W.K. & Kim, S. (1970). „Solubilization and partial purification of protein methylase 3 from calf thymus nuclei”. J. Biol. Chem. 245: 6010—6015. PMID 5484460.
- ^ Venkatesan, M. & McManus, I.R. (1979). „Partial purification and characterization of a protein lysine methyltransferase from plasmodia of Physarum polycephalum”. Biochemistry. 18: 5365—5371. PMID 391266.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Histone-lysine+N-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
