Opioid

Opioid je hemijsko jedinjenje koje se vezuje za opioidne receptore, koji se nalaze prvenstveno u centralnom nervnom sistemu i gastrointestinalnom traktu. Ovi receptori u tim organima posreduju blagotvorne kao i sporedne efekte opioida.

Analgetski efekti opioida dolaze os umanjenog percepcije bola, umanjene reakcije na bol kao i povećane tolerancije bola. Nepoželjni efekti opioida su sedacija, respiratorna depresija, i konstipacija. Opioidi mogu da uzrokuju umanjenje kašlja. Fizička zavisnost može da se razvije tokom njihove administracije, koja dovodi do sindroma povlačenja kod naglog prekida upotrebe. Opioidi mogu da proizvedu osećanje euforije.

Vidi još

• Psihoaktivni lek
• Opijati
• Upoređenje opijata
• Opioidni receptori

Dodatna literatura

• Palliativedrugs.com Palliative Care Formulary and bulletin board with over 22,000 worldwide registered. Free to register.
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