Kortisol sulfotransferaza
Kortisol sulfotransferaza (EC 2.8.2.18, glukokortikosteroidna sulfotransferaza, glukokortikoidna sulfotransferaza) je enzim sa sistematskim imenom 3'-fosfoadenilil-sulfat:kortizol 21-sulfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Kortisol sulfotransferaza | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifikatori | |||||||||
EC broj | 2.8.2.18 | ||||||||
CAS broj | 59782-20-6 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
|
- 3'-fosfoadenilil sulfat + kortizol adenozin 3',5'-bisfosfat + kortizol 21-sulfat
Reference
uredi- ^ Singer, S.S. & Brill, B. (1982). „Enzymatic sulfation of steroids. XVII. The properties of the glucocorticoid sulfotransferase activity of guinea pig liver cytosol”. Biochim. Biophys. Acta. 712: 590—596. PMID 6957246.
- ^ Singer, S.S., Giera, D., Johnson, J. and Sylvester, S. (1976). „Enzymatic sulfation of steroids: I. The enzymatic basis for the sex difference in cortisol sulfation by rat liver preparations”. Endocrinology. 98: 963—974. PMID 1278101.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
uredi- Cortisol+sulfotransferase на US National Library of Medicine Medical Subject Headings (MeSH)