Lizinska karboksipeptidaza
Lizinska karboksipeptidaza (EC 3.4.17.3, karboksipeptidaza N, argininska karboksipeptidaza, kininaza I, anafilatoksinski inaktivator, karboksipeptidaza B plazme, faktor konverzije kreatinske kinaze, bradikinaza, kininaza Ia, hipurilizinska hidrolaza, enzim razlaganja bradikinina, protaminaza, CPaze N, kreatinin kinazna konvertaza, peptidilna-L-lizin(-L-arginin) hidrolaza, CPN) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Lizinska karboksipeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.17.3 | ||||||||
| CAS broj | 9013-89-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Odvajanje C-terminalne bazne aminokiseline, preferentno lizina.
Ovaj cinkov enzim je prisutan u plazmi.
Reference
уреди- ^ Plummer, T.H., Jr. & Erdös, E.G. (1981). „Human plasma carboxypeptidase N”. Methods Enzymol. 80: 442—449. PMID 7341915.
- ^ Levin, Y., Skidgel, R.A. and Erdös, E.G. (1982). „Isolation and characterization of the subunits of human plasma carboxypeptidase N (kininase I)”. Proc. Natl. Acad. Sci. USA. 79: 4618—4622. PMID 6750606.
- ^ Skidgel, R.A. (1988). „Basic carboxypeptidases: regulators of peptide hormone activity”. Trends Pharmacol. Sci. 9: 301—303. PMID 3074547.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Lysine+carboxypeptidase на US National Library of Medicine Medical Subject Headings (MeSH)
