'''Citikolin''' (''[[citidin difosfat]]-holin'', ''CDP-holin'', ''citidin 5'-difosfoholin'') je [[psihostimulans]]/[[nutropik]]. On je intermedijar u generaciji [[fosfatidilholin]]a iz [[holin]]a.
Ispitivanja sugerišu da CDP-holin suplementi povećavaju gustine dopaminskog receptora,<ref>{{cite journal |vauthors=Giménez R, Raïch J, Aguilar J |title=Changes in brain striatum dopamine and acetylcholine receptors induced by chronic CDP-choline treatment of aging mice |journal=British Journal of Pharmacology |volume=104 |issue=3 |pages=575–8 |year=1991 |month=November |pmid=1839138 |pmc=1908237}}</ref> i da pomažu u sprečavanju gubljenja memorije uzrokovanog lošim uslovima životne sredine.<ref>{{cite journal |vauthors=Teather LA, Wurtman RJ |title=Dietary CDP-choline supplementation prevents memory impairment caused by impoverished environmental conditions in rats |journal=Learning & Memory |volume=12 |issue=1 |pages=39–43 |year=2005 |pmid=15647594 |pmc=548494 |doi=10.1101/lm.83905}}</ref> Preliminarna ispitivanja su utvrdila da citikolinski suplementi pomažu u poboljšanju fokusa i mentalne energije, te da potencijalno mogu da budu korisni u tretmanu deficita koncentracije.<ref>{{cite news |url=http://www.smh.com.au/articles/2008/02/24/1203788130776.html |title=Supplement naturally boosts ageing brain power |date = 25. 02. 2008. |work= Sydney Morning Herald |accessdate = 28. 07. 2009.}}</ref><ref>{{cite journal |author1=Silveri MM |author2=Dikan J |author3=Ross AJ |author4=''et al.'' |title=Citicoline enhances frontal lobe bioenergetics as measured by phosphorus magnetic resonance spectroscopy |journal=NMR in Biomedicine |volume=21 |issue=10 |pages=1066–75 |year=2008 |month=November |pmid=18816480 |doi=10.1002/nbm.1281}}</ref> Citikolin isto tako povišava nivo [[ACTH]]-a nezavisno od nivoa [[Kortikotropin-oslobađajući hormon|CRH]].<ref>{{cite journal |vauthors=Cavun S, Savci V |title=CDP-choline increases plasma ACTH and potentiates the stimulated release of GH, TSH and LH: the cholinergic involvement |journal=Fundamental & Clinical Pharmacology |volume=18 |issue=5 |pages=513–23 |year=2004 |month=October |pmid=15482372 |doi=10.1111/j.1472-8206.2004.00272.x}}</ref>
