Supstanca P — разлика између измена
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U [[neuronauka|neuronauci]] '''supstanca P''' (SP) je [[neuropeptid]]: undekapeptid koji funkcioniše kao [[neurotransmiter]] i [[neuromodulator]].<ref name="pmid11378438">{{cite journal | author = Harrison S, Geppetti P | title = Substance p | journal = The International Journal of Biochemistry & Cell Biology | volume = 33 | issue = 6 | pages = 555–76 | year = 2001 | month = June | pmid = 11378438 | doi = 10.1016/S1357-2725(01)00031-0 | url = }}</ref><ref name="pmid14754378">{{cite journal | author = Datar P, Srivastava S, Coutinho E, Govil G | title = Substance P: structure, function, and therapeutics | journal = Current topics in medicinal chemistry | volume = 4 | issue = 1 | pages = 75–103 | year = 2004 | pmid = 14754378 | doi = 10.2174/1568026043451636| url = http://www.bentham-direct.org/pages/content.php?CTMC/2004/00000004/00000001/0009R.SGM }}</ref> Ovaj molekul pripada familiji [[tahikinin]]skih neuropeptida. Supstanca P i njen blisko srodni neuropeptid [[neurokinin A]] (NKA) nastaju iz poliproteinskog prekursora nakon diferencijalnog splajsovanja gena preprotahikinina A. Aminokiselinska sekvenca supstance P je<ref name="pmid">{{cite journal | author = Chang MM, Leeman SE, Niall HD | title = Amino-acid sequence of substance P | journal = Nature: New Biology | volume = 232 | issue = 29 | pages = 86–7 | year = 1971 | month = July | pmid = | doi = | url = | issn = | accessdate =
* -{[[Arginin|Arg]] [[Prolin|Pro]] [[Lizin|Lys]] [[Prolin|Pro]] [[Glutamin|Gln]] [[Glutamin|Gln]] [[Fenilalanin|Phe]] [[Fenilalanin|Phe]] [[Glicin|Gly]] [[Leucin|Leu]] [[Metionin|Met]]}-
Supstanca P se oslobađa iz završetaka specifičnih senzornih nerava. Nađena je u mozgu i kičmenoj moždini, i učestvuje u inflamatornim procesima i senzaciji [[bola]].
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==Spoljašnje veze==
* {{cite web | url = http://www.fibromyalgiasupport.com/library/showarticle.cfm/id/3097 | title = Neurochemical Substance P is Key to Understanding Pain Process | author = Russell J | authorlink = | coauthors = | date =
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