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Ред 1:
[[Датотека:protein pattern analyzer.jpg|300px|thumb|right|Robotska priprema uzoraka za [[Matrično aktivirana laserska desorpcija/jonizacija|MALDI]] [[masena spektrometrija|masenu spektrometriju]].]]
 
'''Proteomika''' je izučavanje [[protein]]a velikih razmera sa fokusom na njihovu [[proteinska struktura|strukturu]] i [[funkcionalna genomika|funkcije]].<ref name="pmid9740045">{{cite journal |author=Anderson NL, Anderson NG |title=Proteome and proteomics: new technologies, new concepts, and new words |journal=Electrophoresis |volume=19 |issue=11 |pages=1853–611853-61 |year=1998 |pmid=9740045 |doi=10.1002/elps.1150191103}}</ref><ref name="pmid10189717">{{cite journal |author=Blackstock WP, Weir MP |title=Proteomics: quantitative and physical mapping of cellular proteins |journal=Trends Biotechnol. |volume=17 |issue=3 |pages=121–7121-7 |year=1999 |pmid=10189717| doi = 10.1016/S0167-7799(98)01245-1}}</ref> Proteini su vitalni delovi živih organizama. Oni su glavne komponente fizioloških [[metabolički put|metaboličkih puteva]] u [[ćelija (biologija)|ćelijama]]. Termin ''proteomika'' je formiran [[1997]]<ref>{{cite journal |author=P. James |title=Protein identification in the post-genome era: the rapid rise of proteomics.|journal=Quarterly reviews of biophysics|volume=30 |issue=4|pages=279–331279-331 |year=1997 |pmid=9634650 |doi=10.1017/S0033583597003399}}</ref> po analogiji sa [[genomika|genomikom]], studijom [[genom]]a. Reč ''proteom'' je mešavina reči '''''prote'''in'' i ''gen'''om''''', koju je formirao [[Mark Vilkins (genetičar)|Mark Vilkins]] [[1994]].<ref name="wilkins1996">{{cite journal |author=Marc R. Wilkins, Christian Pasquali, Ron D. Appel, Keli Ou, Olivier Golaz, Jean-Charles Sanchez, Jun X. Yan, Andrew. A. Gooley, Graham Hughes, Ian Humphery-Smith, Keith L. Williams & Denis F. Hochstrasser|title=From Proteins to Proteomes: Large Scale Protein Identification by Two-Dimensional Electrophoresis and Arnino Acid Analysis|journal=Nature Biotechnology |volume=14 |issue=1 |pages=61–6561-65 |year=1996 |pmid=9636313 |doi=10.1038/nbt0196-61}}</ref><ref>[http://www.babs.unsw.edu.au/directory.php?personnelID=12 UNSW Staff Bio: Professor Marc Wilkins]</ref>
 
[[Proteom]] je celokupan set proteina<ref name="wilkins1996" /> koji jedan organizam proizvodi ili modifikuje. Njegov sadržaj varira s vremenom i u zavisnosti od raznih uslova, stresova, kojima su ćelija ili ogranizam izloženi. Proteomika je interdisciplinarni domen koji je znatnim delom formiran na bazi istraživanja i razvoja [[Projekat ljudskog genoma|Projekta ljudskog genoma]]. Ona obuhvata naučna istraživanja i ispitivanja proteoma sa sveobuhvatnog stanovišta intracelularne proteinske kompozicije, strukture, i njegovih jedinstvenih parterna dejstva. Proteomioka je važna komponenta funkcionalne genomike.
Ред 13:
{{Refbegin|2}}
* Belhajjame, K. et al. [http://www.allhands.org.uk/2005/proceedings/papers/525.pdf Proteome Data Integration: Characteristics and Challenges]. Proceedings of the UK e-Science All Hands Meeting, ISBN 1-904425-53-4, September 2005, Nottingham, UK.
* {{Cite book |ref= harv|author=Twyman RM |title=Principles Of Proteomics (Advanced Text Series) |publisher=BIOS Scientific Publishers |location=Oxford, UK |year=2004 |isbnid=ISBN 1-85996-273-4 }} (covers almost all branches of proteomics)
* {{Cite book |ref= harv|author=Naven T, Westermeier R |title=Proteomics in Practice: A Laboratory Manual of Proteome Analysis |publisher=Wiley-VCH |location=Weinheim |year=2002 |isbnid=ISBN 3-527-30354-5 }} (focused on 2D-gels, good on detail)
* {{Cite book |ref= harv|author=Liebler DC |title=Introduction to proteomics: tools for the new biology |publisher=Humana Press |location=Totowa, NJ |year=2002 |isbnid=ISBN 0-89603-992-7 }} ISBN 0-585-41879-9 (electronic, on Netlibrary?), ISBN 0-89603-991-9 hbk
* {{Cite book |ref= harv|author=Wilkins MR, Williams KL, Appel RD, Hochstrasser DF |title=Proteome Research: New Frontiers in Functional Genomics (Principles and Practice) |publisher=Springer |location=Berlin |year=1997 |isbnid=ISBN 3-540-62753-7 }}
* {{cite journal |author=Arora PS, Yamagiwa H, Srivastava A, Bolander ME, Sarkar G |title=Comparative evaluation of two two-dimensional gel electrophoresis image analysis software applications using synovial fluids from patients with joint disease |journal=J Orthop Sci |volume=10 |issue=2 |pages=160–6160-6 |year=2005 |pmid=15815863 |doi=10.1007/s00776-004-0878-0 |url=http://www.springerlink.com/openurl.asp?genre=article&doi=10.1007/s00776-004-0878-0}}
* Rediscovering Biology Online Textbook. Unit 2 Proteins and Proteomics. 1997–2006.
* {{Cite book |ref= harv|author=Weaver RF |title=Molecular biology |publisher=McGraw-Hill |location=New York |year=2005 |pages=840–9840-9 |isbnid=ISBN 0-07-284611-9 |edition=3rd}}
* {{Cite book |ref= harv|author=Reece J, Campbell N |title=Biology |publisher=Benjamin Cummings |location=San Francisco |year=2002 |pages=392–3392-3 |isbnid=ISBN 0-8053-6624-5 |edition=6th}}
* {{cite journal |author=Hye A |title=Proteome-based plasma biomarkers for Alzheimer's disease |journal=Brain |volume=129 |issue=Pt 11 |pages=3042–503042-50 |year=2006 |month= November|pmid=17071923 |doi=10.1093/brain/awl279 |author-separator=, |last2=S|first2=Lynham|last3=M|first3=Thambisetty|display-authors=3 |last4=Causevic |first4=M. |last5=Campbell |first5=J. |last6=Byers |first6=H. L. |last7=Hooper |first7=C. |last8=Rijsdijk |first8=F. |last9=Tabrizi |first9=S. J. }}
* {{cite journal |author=Perroud B |title=Pathway analysis of kidney cancer using proteomics and metabolic profiling |journal=Mol Cancer |volume=5 |issue= |pages=64 |year=2006 |pmid=17123452 |pmc=1665458 |doi=10.1186/1476-4598-5-64 |author-separator=, |last2=J|first2=Lee|last3=N|first3=Valkova|display-authors=3 |last4=Dhirapong |first4=Amy |last5=Lin |first5=Pei-Yin |last6=Fiehn |first6=Oliver |last7=Kültz |first7=Dietmar |last8=Weiss |first8=Robert H }}
* {{cite journal |author=Yohannes E, Chang J, Christ GJ, Davies KP, Chance MR |title=Proteomics analysis identifies molecular targets related to diabetes mellitus-associated bladder dysfunction |journal=Mol. Cell Proteomics |volume=7 |issue=7 |pages=1270–851270-85 |year=2008 |month= July|pmid=18337374 |doi=10.1074/mcp.M700563-MCP200 |pmc=2493381 }}.
* {{cite journal |author=Macaulay IC, Carr P, Gusnanto A, Ouwehand WH, Fitzgerald D, Watkins NA |title=Platelet genomics and proteomics in human health and disease |journal=J Clin Invest. |volume=115 |issue=12 |pages=3370–73370-7 |year=2005 |month= December|pmid=16322782 |pmc=1297260 |doi=10.1172/JCI26885 }}
* {{cite journal |author=Rogers MA |title=Proteomic profiling of urinary proteins in renal cancer by surface enhanced laser desorption ionization and neural-network analysis: identification of key issues affecting potential clinical utility |journal=Cancer Res. |volume=63 |issue=20 |pages=6971–836971-83 |date = 15. 10. 2003.|pmid=14583499 |url=http://cancerres.aacrjournals.org/cgi/pmidlookup?view=long&pmid=14583499 |author-separator=, |last2=P|first2=Clarke|last3=J|first3=Noble|display-authors=3 |last4=Munro |first4=NP |last5=Paul |first5=A |last6=Selby |first6=PJ |last7=Banks |first7=RE }}
* {{cite journal |author=Vasan RS |title=Biomarkers of cardiovascular disease: molecular basis and practical considerations |journal=Circulation |volume=113 |issue=19 |pages=2335–622335-62 |year=2006 |month=May |pmid=16702488 |doi=10.1161/CIRCULATIONAHA.104.482570 }}
* [http://medlib.med.utah.edu/WebPath/TUTORIAL/MYOCARD/MYOCARD.html "Myocardial Infarction"]. (Retrieved 29 November 2006)
* Introduction to Antibodies – [http://www.chemicon.com/resource/ANT101/a2C.asp Enzyme-Linked Immunosorbent Assay (ELISA)]. (Retrieved 29 November 2006)
* {{cite journal |author=Decramer S |title=Predicting the clinical outcome of congenital unilateral ureteropelvic junction obstruction in newborn by urinary proteome analysis |journal=Nat Med. |volume=12 |issue=4 |pages=398–400398-400 |year=2006 |month= April|pmid=16550189 |doi=10.1038/nm1384 |url=http://www.nature.com/nm/journal/v12/n4/abs/nm1384.html |author-separator=, |last2=S|first2=Wittke|last3=H|first3=Mischak|display-authors=3 |last4=Zürbig |first4=Petra |last5=Walden |first5=Michael |last6=Bouissou |first6=François |last7=Bascands |first7=Jean-Loup |last8=Schanstra |first8=Joost P}}
* {{cite journal |author=Mayer U |title=Protein Information Crawler (PIC): extensive spidering of multiple protein information resources for large protein sets |journal=Proteomics |volume=8 |issue=1 |pages=42–442-4 |year=2008 |month= January|pmid=18095364 |doi=10.1002/pmic.200700865 }}
* Jörg von Hagen, VCH-Wiley 2008 ''Proteomics Sample Preparation. ISBN 978-3-527-31796-7.
{{Refend}}
Преузето из „https://sr.wikipedia.org/wiki/Proteomika”