Galaktozilgalaktozilksilozilprotein 3-beta-glukuronoziltransferaza 3 je enzim koji je kod ljudi kodiran genom B3GAT3.[4][5]

B3GAT3
Available structures
PDBPretraga ortologa: PDBe RCSB
Identifikatori
AlijasiB3GAT3
Spoljašnji IDOMIM: 606374 MGI: 1919977 HomoloGene: 56554 GeneCards: B3GAT3
Obrazac RNK izražavanja


More reference expression data
Ortolozi
VrsteČovekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001288721
NM_001288722
NM_001288723
NM_012200

NM_024256

RefSeq (protein)

NP_001275650
NP_001275651
NP_001275652
NP_036332

NP_077218

Location (UCSC)n/aChr 19: 8.9 – 8.9 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Protein kodiran ovim genom je član porodice gena glukuroniltransferaze, enzima koji pokazuju strogu specifičnost akceptora, prepoznajući nereducirajuće terminalne šećere i njihove anomerne veze. Ovaj genski proizvod katalizuje formiranje veze glikozaminoglikan-protein putem reakcije transfera glukuronila u završnom koraku biosinteze regiona veze proteoglikana.[5]

References

уреди
  1. ^ а б в GRCm38: Ensembl release 89: ENSMUSG00000071649 - Ensembl, May 2017
  2. ^ „Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  3. ^ „Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Kitagawa H, Tone Y, Tamura J, Neumann KW, Ogawa T, Oka S, Kawasaki T, Sugahara K (април 1998). „Molecular cloning and expression of glucuronyltransferase I involved in the biosynthesis of the glycosaminoglycan-protein linkage region of proteoglycans”. J Biol Chem. 273 (12): 6615—8. PMID 9506957. doi:10.1074/jbc.273.12.6615 . 
  5. ^ а б „Entrez Gene: B3GAT3 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)”. 

Literatura

уреди

Spoljašnje veze

уреди
  • Human B3GAT3 genome location and B3GAT3 gene details page in the UCSC Genome Browser.
  • Overview of all the structural information available in the PDB for UniProt: O94766 (Human Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (B3GAT3)) at the PDBe-KB.