Bay R 1531
Bay R 1531 je triciklični triptaminski derivat koji deluje kao selektivni agonist serotoninskog receptora 5-HT1A. On je neuspešno istraživan za tretman moždanog udara. Bay R 1531 se i dalje koristi u naučnim istraživanjima.[1][2][3][4]
IUPAC ime | |
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1,3,4,5-tetrahidro-6-metoksi-N,N-dipropil-benz[cd]indol-4-amin | |
Identifikatori | |
CAS broj | 98770-54-8 |
ATC kod | none |
PubChem | CID 127153 |
ChemSpider | 112872 |
Hemijski podaci | |
Formula | C18H28N2O |
Molarna masa | 288,427 g/mol |
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Reference uredi
- ^ Bielenberg GW, Burkhardt M. 5-hydroxytryptamine1A agonists. A new therapeutic principle for stroke treatment. Stroke. 1990 Dec;21(12 Suppl):IV161-3. PMID 2148035
- ^ Critchley, M. A.; Njung'e, K.; Handley, S. L. (1992). „Actions and some interactions of 5-HT1A ligands in the elevated X-maze and effects of dorsal raphe lesions”. Psychopharmacology. 106 (4): 484—490. PMID 1533721. S2CID 8404850. doi:10.1007/BF02244819.
- ^ Canto de Souza A, Nunes de Souza RL, Péla IR, Graeff FG. High intensity social conflict in the Swiss albino mouse induces analgesia modulated by 5-HT1A receptors. Pharmacology, Biochemistry and Behavior. 1997 Mar;56(3):481-6. PMID 9077586}-
- ^ Canto-de-Souza A, Nunes de Souza RL, Pelá IR, Graeff FG. Involvement of the midbrain periaqueductal gray 5-HT1A receptors in social conflict induced analgesia in mice. European Journal of Pharmacology. 1998 Mar 26;345(3):253-6. PMID 9592023