6-Hloro-2-aminotetralin (6-CAT) je lek koji deluje kao selektivni agens oslobađanja serotonina (SSRA) i mogući entaktogen kod ljudi.[1][2] To je kruti analog para-hloroamfetamina (PCA).[1]

6-CAT
IUPAC ime
6-hloro-1,2,3,4-tetrahidronaftalen-2-amin
Klinički podaci
Način primeneOralno
Pravni status
Pravni status
  • Uncontrolled
Identifikatori
CAS broj60480-00-4
PubChemCID 16244336
ChemSpider11269876 ДаY
Hemijski podaci
  • C1CC2=C(CC1N)C=CC(=C2)Cl
  • InChI=1S/C10H12ClN/c11-9-3-1-8-6-10(12)4-2-7(8)5-9/h1,3,5,10H,2,4,6,12H2 ДаY
  • Key:CJRJTCMSQLEPFQ-UHFFFAOYSA-N ДаY

According to Nichols et al.,[3] 6-CAT is a non-neurotoxic analog of PCA.

Vidi još

уреди

Reference

уреди
  1. ^ а б Fuller RW, Perry KW, Baker JC, Molloy BB (новембар 1974). „6-Chloro-2-aminotetralin, a rigid Conformational analog of 4-chloroamphetamine: pharmacologic properties of it and related compounds in rats”. Archives Internationales de Pharmacodynamie et de Therapie. 212 (1): 141—53. PMID 4455127. 
  2. ^ Fuller RW, Wong DT, Snoddy HD, Bymaster FP (1977). „Comparison of the effects of 6-chloro-2-aminotetralin and of ORG 6582, a related chloroamphetamine analog, on brain serotonin metabolism in rats”. Biochemical Pharmacology. 26 (1): 1,333—1,337. doi:10.1016/0006-2952(77)90094-6. 
  3. ^ Johnson MP, Frescas SP, Oberlender R, Nichols DE (мај 1991). „Synthesis and pharmacological examination of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: similarities to 3,4-(methylenedioxy)methamphetamine (MDMA)”. Journal of Medicinal Chemistry. 34 (5): 1662—8. PMID 1674539. doi:10.1021/jm00109a020.