|
| imagename =
| drug_name = Eritromicin
| caption =
<!-- Clinical data -->
| metabolism =
| elimination_half-life = 0,8 - 3 sata
| excretion =
<!-- Identifiers -->
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 48923
| synonyms =
<!-- Chemical data -->
| sec_combustion =
}}
'''Eritromicin''' je [[makrolid|makrolidni antibiotik]] koji formira vrsta -{''Streptomyces erythreus''}-. On inhibira bakterijsku sintezu proteina vezivanjem za bakterijske -[50S]- [[Ribozom|ribozomalneribozom]]alne podjedinice. Njegovim vezivanjem se inhibira dejstvo [[peptidil transferaze]] i time se ometa translokacija [[aminokiselina]] tokom [[Транслација (генетика)|translacije]] i formiranja proteina.<ref>-{Kanazawa S, Ohkubo T, Sugawara K: The effects of grapefruit juice on the pharmacokinetics of erythromycin. Eur J Clin Pharmacol. 2001 Jan-Feb;56(11):799-803. [[PubMed|PMID]] [http://www.ncbi.nlm.nih.gov/pubmed/11294369 11294369]}-</ref><ref>-{Ogwal S, Xide TU: Bioavailability and stability of erythromycin delayed release tablets. Afr Health Sci. 2001 Dec;1(2):90-6. [[PubMed|PMID]] [http://www.ncbi.nlm.nih.gov/pubmed/12789122 12789122]}-</ref><ref>-{Okudaira T, Kotegawa T, Imai H, Tsutsumi K, Nakano S, Ohashi K: Effect of the treatment period with erythromycin on cytochrome P450 3A activity in humans. J Clin Pharmacol. 2007 Jul;47(7):871-6. [[PubMed|PMID]] [http://www.ncbi.nlm.nih.gov/pubmed/17585116 17585116]}-</ref><ref>{{cite journal |title = DrugBank 3.0: a comprehensive resource for omics research on drugs |author vauthors= Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS |journal = Nucleic Acids Res. |year = 2011 |volume = 39 |issue = Database issue |pages = D1035-41 | pmid =21059682}}</ref><ref>{{cite journal |title = DrugBank: a knowledgebase for drugs, drug actions and drug targets |author = Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (Nucleic Acids Res) |year = 2008 |volume = 36 |issue = Database issue |pages = D901-6 |pmid = 18048412}}</ref>
== Reference ==
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