Vitamin D5 je oblik vitamina D.

Vitamin D5
Nazivi
IUPAC naziv
(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4S)-4-etil-1,5-dimetilheksil]-7a-metil-2,3,3a,5,6,7-heksahidro-1H-inden-4-iliden]etiliden]-4-metilen-1-cikloheksanol
Identifikacija
3D model (Jmol)
ChemSpider
  • O[C@@H]1CC(\C(=C)CC1)=C\C=C2/CCC[C@]3([C@H]2CC[C@@H]3[C@H](C)CC[C@H](CC)C(C)C)C
Svojstva
C29H48O
Molarna masa 412,69
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
ДаY verifikuj (šta je ДаYНеН ?)
Reference infokutije

Analogna jedinjenja su predložena za upotrebu kao antitumorski agensi.[3][4][5]

Reference

уреди
  1. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди
  2. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 
  3. ^ Mehta RG; Moriarty RM; Mehta RR; et al. (1997). „Prevention of preneoplastic mammary lesion development by a novel vitamin D analogue, 1alpha-hydroxyvitamin D5”. J. Natl. Cancer Inst. 89 (3): 212—8. PMID 9017001. doi:10.1093/jnci/89.3.212. 
  4. ^ Murillo G, Mehta RG (2005). „Chemoprevention of chemically-induced mammary and colon carcinogenesis by 1alpha-hydroxyvitamin D5”. J. Steroid Biochem. Mol. Biol. 97 (1-2): 129—36. PMID 16051482. doi:10.1016/j.jsbmb.2005.06.008. 
  5. ^ Mehta RG (2004). „Stage-specific inhibition of mammary carcinogenesis by 1alpha-hydroxyvitamin D5”. Eur. J. Cancer. 40 (15): 2331—7. PMID 15454260. doi:10.1016/j.ejca.2004.05.025. 

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уреди