MK-912 je agonist alfa adrenergičkog receptora.[3]

MK-912
Nazivi
Preferisani IUPAC naziv
(2S,12bS)-1',3'-dimetilspiro[1,3,4,6,7,12b-heksahidro-[1]benzofuro[2,3-a]hinolizin-2,4'-1,3-diazinan]-2'-on
Drugi nazivi
1',3'-dimetilspiro(1,3,4,5',6,6',7,12b-oktahidro-2H-benzo(b)furo(2,3-a)hinolizin)-2,4'-pirimidin-2'-on • L 657,743 • L 657743 • L-657,743 • L-657,743-002W • MK 912 • MK-912 • 111466-41-2 • UNII-UT87RB8I1V • MK-912 • UT87RB8I1V • L 657743 • L-657,743 • MK912 • L-657,743-002W • L 657,743 • MK-912 FREE BASE • CHEMBL1257057 • SCHEMBL15902756 • GTPL12577 • DTXSID60912170 • Q27291261
Identifikacija
3D model (Jmol)
UNII
  • CN1CCC2(CCN3CCC4=C(C3C2)OC5=CC=CC=C45)N(C1=O)C
Svojstva
C20H25N3O2
Molarna masa 339,44 g·mol−1
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
Reference infokutije

Reference

уреди
  1. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди
  2. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 
  3. ^ Richard G W Proudman; Juliana Akinaga; Jillian G Baker (2022). „The affinity and selectivity of α-adrenoceptor antagonists, antidepressants and antipsychotics for the human α2A, α2B, and α2C-adrenoceptors and comparison with human α1 and β-adrenoceptors”. Pharmacol Res Perspect. 10 (2): e00936. doi:10.1002/prp2.936.