SL-75102, ili progabidna kiselina, je aktivni metabolit progabida i antikonvulsantni agonist GABA receptora .[3][4]

SL-75102
Nazivi
IUPAC naziv
4-[[(4-Hlorofenil)-(3-fluoro-6-oksocikloheksa-2,4-dien-1-iliden)metil]amino]butanoinska kiselina
Drugi nazivi
Progabidna kiselina; LS-187121; SL-75-102-00
Identifikacija
3D model (Jmol)
ChEBI
  • C1=CC(=CC=C1C(=C2C=C(C=CC2=O)F)NCCCC(=O)O)Cl
Svojstva
C17H15ClFNO3
Molarna masa 335,76 g·mol−1
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
Reference infokutije

Reference

уреди
  1. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди
  2. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 
  3. ^ „Progabide and SL 75102 binding to plasma proteins and red blood cells in humans”. Int J Clin Pharmacol Ther Toxicol. 25 (4): 178—84. 1987. PMID 3583466. 
  4. ^ „Anticonvulsant effect of SL 75 102 in adult and immature rats”. Physiol Res. 46 (1): 73—6. 1997. PMID 9728525.