BD-1063
BD-1063 je antagonist sigma receptora koji je selektivan za σ1 tip. On blokira MDMA efekte u studijama na životinjama,[1] i umanjuje unos alkohola u modelima alkoholizma.[2]
 | |
| IUPAC ime | |
|---|---|
1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine | |
| Identifikatori | |
| CAS broj | 150208-28-9  |
| ATC kod | none |
| PubChem | CID 574780 |
| Hemijski podaci | |
| Formula | C13H18Cl2N2 |
| Molarna masa | 273.201 g/mol |
| |
Reference
уреди- ^ Brammer MK, Gilmore DL, Matsumoto RR (2006). „Interactions between 3,4-methylenedioxymethamphetamine and sigma1 receptors”. European Journal of Pharmacology. 553 (1-3): 141—5. PMC 1780037
. PMID 17070798. doi:10.1016/j.ejphar.2006.09.038.
- ^ Sabino V, Cottone P, Zhao Y, Iyer MR, Steardo L, Steardo L, Rice KC, Conti B, Koob GF, Zorrilla EP (2009). „The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking”. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34 (6): 1482—93. PMC 2669694 . PMID 18946467. doi:10.1038/npp.2008.192.
 | Molimo Vas, obratite pažnju na važno upozorenje u vezi sa temama iz oblasti medicine (zdravlja). |
